Mouse SGOL1 Recombinant Protein – Cat# MBS1306873

Shugoshin-Like 1 (SGOL1) Mouse Recombinant Protein

Name: SGOL1 Recombinant Protein; Shugoshin-Like 1; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS1306873
Price: 1320 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1306873

MBS1306873 is a recombinant protein targeting Sgol1. Also known as Recombinant Mouse Shugoshin-like 1 (Sgol1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1320 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Shugoshin-like 1 (Sgol1), Recombinant Protein

Full Product Name

Recombinant Mouse Shugoshin-like 1 (Sgol1)

Product Gene Name

Sgol1 recombinant protein

Product Synonym Gene Name

Sgol1

Sequence

MAKERCQKRS FQDTLEDIKN RMKEKRNKNL AGIGKRKSFI VAPGQVPTNT ATLLRYYQDN NRLLVLALEN EKSKVREAQD VILQLRKECY YLTCQLYALK EKLTSRQSEE TTQNWKGRPS DVVSSIDNTT RDLSGKSLQQ IAVEETDCPY QTTEPSPAVT PETQGCDFDS GKVESTDEVL PRTISIRRHL RKDFSNISHS TTLEDCKASP RVAQSLEVKG SRCREVTVTL HRLENVCLWN KDQISLCSRL INPAKITETE VILSSKPEQI ESKHKRARKR RAEQRRTKQR CKSKSSLRSK GNKNKDKQGL PPTTLDGGIG SCDAYDFNLK GTVHPTPFRQ KMNNGCNKET DSSNSEVSDL ECSTSEDESD DLYLPPSKRL RDYRESERAV TRPRSKRGLQ YPDGKERKEV LPSTAPTGIP PETQESPRCS LKDVTNILQC PRVKIRKPSL PPKRREDSPA VALTKRRCST IKSYKEPTLA SKLRRGDPFT DLCFLNSPIF KQKRGMRCPK RRTKQTQ

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

19,672 Da

Sequence Positions

1-517, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q9CXH7

Species

Mouse

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Sgol1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Sgol1. It may not necessarily be applicable to this product.

NCBI GI #

13386294

NCBI GeneID

72415

NCBI Accession #

NP_082508.1

UniProt Primary Accession #

Q9CXH7

UniProt Secondary Accession #

Q3U4K4; Q588H1; Q8BKW2

UniProt Related Accession #

Q9CXH7

GenBank Nucleotide #

NM_028232.2

NCBI Official Full Name

shugoshin 1

NCBI Official Synonym Full Names

shugoshin 1

NCBI Official Symbol

Sgo1

NCBI Official Synonym Symbols

Sgol1; C81037; 3300001M08Rik

UniProt Protein Name

Shugoshin 1

UniProt Synonym Protein Names

Shugoshin-like 1

UniProt Gene Name

Sgo1

NCBI Protein Information

shugoshin 1; shugoshin-like 1

UniProt Comments for Sgol1

Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Involved in centromeric enrichment of AUKRB in prometaphase.

Research Articles on Sgol1

1. Study shows Sgo1 expression in heart, gut, eye and other central nervous system tissue during development and post-development. It demonstrates Sgo1 localization in cytoplasmic region in nucleated cells in select organs.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Sgol1 recombinant protein

Products by Pathway	Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
Mitotic Anaphase Pathway antibodies	Mitotic Anaphase Pathway Diagram
Mitotic Metaphase And Anaphase Pathway antibodies	Mitotic Metaphase And Anaphase Pathway Diagram
Mitotic Prometaphase Pathway antibodies	Mitotic Prometaphase Pathway Diagram
Oocyte Meiosis Pathway antibodies	Oocyte Meiosis Pathway Diagram
Oocyte Meiosis Pathway antibodies	Oocyte Meiosis Pathway Diagram
Resolution Of Sister Chromatid Cohesion Pathway antibodies	Resolution Of Sister Chromatid Cohesion Pathway Diagram
Separation Of Sister Chromatids Pathway antibodies	Separation Of Sister Chromatids Pathway Diagram

Diseases associated with Sgol1 recombinant protein

Disease Name	Pubmed Publications
Intestinal Diseases Antibodies	>3 publications with Sgol1 and Intestinal Diseases
Lung Neoplasms Antibodies	>2 publications with Sgol1 and Lung Neoplasms
Liver Diseases Antibodies	>1 publications with Sgol1 and Liver Diseases
Fatty Liver Antibodies	>1 publications with Sgol1 and Fatty Liver
Necrosis Antibodies	>1 publications with Sgol1 and Necrosis

Organs/Tissues associated with Sgol1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>2 publications with Sgol1 and Lung
Blood Antibodies	>2 publications with Sgol1 and Blood
Bone Marrow Antibodies	>2 publications with Sgol1 and Bone Marrow
Bone Antibodies	>2 publications with Sgol1 and Bone
Liver Antibodies	>1 publications with Sgol1 and Liver