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Cytosolic Acyl Coenzyme A Thioester Hydrolase (ACOT7) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1307443

This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively… More details

$1115 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cytosolic acyl coenzyme A thioester hydrolase (Acot7), Recombinant Protein
Full Product Name
Recombinant Mouse Cytosolic acyl coenzyme A thioester hydrolase (Acot7)
Product Gene Name
Acot7 recombinant protein
Product Synonym Gene Name
Acot7
Sequence
MKLLVGTLRL WEVGRQVAFS SLTPGQECSG LRKTFWAAMR AVRTRADHQK LGHCVTMGRI MRPDDANVAG NVHGGTILKM IEEAGAIIST RHCNSQNGER CVAALARVER TDFLSPMCIG EVAHVSAEIT YTSKHSVEVQ VHVMSENILT GTKKLTNKAT LWYVPLSLKN VDKVLEVPPI VYLRQEQEEE GRKRYEAQKL ERMETKWRNG DIVQPVLNPE PNTVSYSQSS LIHLVGPSDC TLHGFVHGGV TMKLMDEVAG IVAARHCKTN IVTASVDAIN FHDKIRKGCV ITISGRMTFT SNKSMEIEVL VDADPVVDNS QKRYRAASAF FTYVSLNQEG KPMPVPQLVP ETEDEKKRFE EGKGRYLQMK AKRQGHTEPQ P
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
41,616 Da
Sequence Positions
1-381, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q91V12
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Acot7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Acot7 purchase

MBS1307443 is a recombinant protein targeting Acot7. Also known as Recombinant Mouse Cytosolic acyl coenzyme A thioester hydrolase (Acot7). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Acot7. It may not necessarily be applicable to this product.

NCBI GI #
225690616
NCBI GeneID
70025
NCBI Accession #
NP_001139529.1
UniProt Primary Accession #
Q91V12
UniProt Secondary Accession #
Q3U8C6; Q59HQ2; A2A8K9; A2A8L0; A2A8L2
UniProt Related Accession #
Q91V12
GenBank Nucleotide #
NM_001146057.1
NCBI Official Full Name
cytosolic acyl coenzyme A thioester hydrolase isoform 1
NCBI Official Synonym Full Names
acyl-CoA thioesterase 7
NCBI Official Symbol
Acot7
NCBI Official Synonym Symbols
Act; Ach1; Bach; Lach1; Cte-II; CTE-IIa; 2410041A17Rik
UniProt Protein Name
Cytosolic acyl coenzyme A thioester hydrolase
UniProt Synonym Protein Names
Acyl-CoA thioesterase 7; Brain acyl-CoA hydrolase; BACH; CTE-IIa; CTE-II; Long chain acyl-CoA thioester hydrolase
Protein Family
Cytosolic acyl coenzyme A thioester hydrolase
UniProt Gene Name
Acot7
UniProt Synonym Gene Names
Bach; BACH; CTE-II
NCBI Protein Information
cytosolic acyl coenzyme A thioester hydrolase

UniProt Comments for Acot7

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.
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Research Articles on Acot7

1. downstream effects of LPS-induced induction of ACOT7 and its role in inflammatory settings in myeloid cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Acot7 recombinant protein

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Acyl-CoA Hydrolysis Pathway antibodies  Acyl-CoA Hydrolysis Pathway Diagram

Diseases associated with Acot7 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with Acot7 and Neoplasms
 Fatty Liver Antibodies  >1 publications with Acot7 and Fatty Liver
 Inflammation Antibodies  >1 publications with Acot7 and Inflammation

Organs/Tissues associated with Acot7 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with Acot7 and Brain
 Muscle Antibodies  >2 publications with Acot7 and Muscle
 Heart Antibodies  >2 publications with Acot7 and Heart
 Connective Tissue Antibodies  >1 publications with Acot7 and Connective Tissue
 Liver Antibodies  >1 publications with Acot7 and Liver
 Testis Antibodies  >1 publications with Acot7 and Testis
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