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Putative Ribosomal RNA Methyltransferase 1 (FTSJ1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1308249

This protein is a member of the S-adenosylmethionine-binding protein family. It is a nucleolar protein and may be involved in the processing and modification of rRNA. Three alternatively spliced transcript variants encoding different isoforms have been… More details

$1040 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Putative ribosomal RNA methyltransferase 1 (FTSJ1), Recombinant Protein
Full Product Name
Recombinant Human Putative ribosomal RNA methyltransferase 1 (FTSJ1)
Product Gene Name
FTSJ1 recombinant protein
Product Synonym Gene Name
FTSJ1
Sequence
MGRTSKDKRD VYYRLAKENG WRARSAFKLL QLDKEFQLFQ GVTRAVDLCA APGSWSQVLS QKIGGQGSGH VVAVDLQAMA PLPGVVQIQG DITQLSTAKE IIQHFKGCPA DLVVCDGAPD VTGLHDVDEY MQAQLLLAAL NIATHVLKPG GCFVAKIFRG RDVTLLYSQL QVFFSSVLCA KPRSSRNSSI EAFAVCQGYD PPEGFIPDLS KPLLDHSYDP DFNQLDGPTR IIVPFVTCGD LSSYDSDRSY PLDLEGGSEY KYTPPTQPPI SPPYQEACTL KRKGQLAKEI RPQDCPISRV DTFPQPLAAP QCHTLLAPEM EDNEMSCSP
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
35,867 Da
Sequence Positions
1-329, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
300499
3D Structure
ModBase 3D Structure for Q9UET6
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FTSJ1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FTSJ1 purchase

MBS1308249 is a recombinant protein targeting FTSJ1. Also known as Recombinant Human Putative ribosomal RNA methyltransferase 1 (FTSJ1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for FTSJ1. It may not necessarily be applicable to this product.

NCBI GI #
531990794
NCBI GeneID
24140
NCBI Accession #
NP_001269086.1
UniProt Primary Accession #
Q9UET6
UniProt Secondary Accession #
O75670; B2RCJ0
UniProt Related Accession #
Q9UET6
GenBank Nucleotide #
NM_001282157.1
NCBI Official Full Name
putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase isoform c
NCBI Official Synonym Full Names
FtsJ RNA methyltransferase homolog 1
NCBI Official Symbol
FTSJ1
NCBI Official Synonym Symbols
JM23; MRX9; SPB1; CDLIV; MRX44; TRMT7
UniProt Protein Name
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
UniProt Synonym Protein Names
2'-O-ribose RNA methyltransferase TRM7 homolog
UniProt Gene Name
FTSJ1
NCBI Protein Information
putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase

NCBI Summary for FTSJ1

This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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UniProt Comments for FTSJ1

Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

Research Articles on FTSJ1

1. we have provided strong evidence that human FTSJ1 is required for Cm32 and Gm34 modification of tRNAPhe.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FTSJ1 recombinant protein

 Reference Product  PubMed Publications
 THADA recombinant protein  >1 publications with FTSJ1 and THADA

Diseases associated with FTSJ1 recombinant protein

 Disease Name  Pubmed Publications
 Neurobehavioral Manifestations Antibodies  >11 publications with FTSJ1 and Neurobehavioral Manifestations
 Chromosome Aberrations Antibodies  >3 publications with FTSJ1 and Chromosome Aberrations
 Mental Retardation, X-Linked 9 Antibodies  >3 publications with FTSJ1 and Mental Retardation, X-Linked 9
 Growth Disorders Antibodies  >1 publications with FTSJ1 and Growth Disorders
 Lung Diseases Antibodies  >1 publications with FTSJ1 and Lung Diseases
 Cognition Disorders Antibodies  >1 publications with FTSJ1 and Cognition Disorders
 Learning Disorders Antibodies  >1 publications with FTSJ1 and Learning Disorders

Organs/Tissues associated with FTSJ1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with FTSJ1 and Blood
 Brain Antibodies  >2 publications with FTSJ1 and Brain
 Lung Antibodies  >1 publications with FTSJ1 and Lung
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