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Serine/Threonine-Protein Kinase RIO3 (RIOK3) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1310492

This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The… More details

$1325 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Serine/threonine-protein kinase RIO3 (Riok3), Recombinant Protein
Full Product Name
Recombinant Mouse Serine/threonine-protein kinase RIO3 (Riok3)
Product Gene Name
Riok3 recombinant protein
Product Synonym Gene Name
Riok3
Sequence
MDLVGVSSPE PGPAAAWGPS KCPWATPQNT VSCSLTEVMS EELAKELQLE EEAAAFPEVV VAEGPFISGE NIDTSSDLML AQMLQMEFDR EYDAQLRREE KKFNGDSKVS ISFENYRKVH PFEDSDSSED EVDWQDTRDD PYRPAKPIPT PKKGFIGKGK DITTKHDEVV CGRKNTARME NFAPGFQVGD GIGMDLKLSN HVFNALKQHA YSEERRSARL HEKKEHSTAE KAVDPKTRLL MYKMVNSGML ETITGCISTG KESVVFHAYG GSLEDEKEDG KAIPTECAIK VFKTTLNEFK NRDKYIKDDF RFKDRFSKLN PRKIIRMWAE KEMHNLTRMQ KAGIPCPTVV LLKKHILVMS FIGHDQVPAP KLKEVKLSNE EMKDAYYQTL HLMQQLYNEC TLVHADLSEY NMLWHAGKVW LIDVSQSVEP THPHGLEFLF RDCRNVSQFF QKGGVTEALN ERELFNAVSG LNISADNEAD FLAEIEALEK MNEDHIQKNG RKAASFLKDD GSPPVLSAD
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
58,704 Da
Sequence Positions
1-519, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9DBU3
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Riok3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Riok3 purchase

MBS1310492 is a recombinant protein targeting Riok3. Also known as Recombinant Mouse Serine/threonine-protein kinase RIO3 (Riok3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Riok3. It may not necessarily be applicable to this product.

NCBI GI #
110625737
NCBI GeneID
66878
NCBI Accession #
NP_077144.2
UniProt Primary Accession #
Q9DBU3
UniProt Secondary Accession #
Q3UI51; Q8CIC1
UniProt Related Accession #
Q9DBU3
GenBank Nucleotide #
NM_024182.4
NCBI Official Full Name
serine/threonine-protein kinase RIO3
NCBI Official Synonym Full Names
RIO kinase 3
NCBI Official Symbol
Riok3
NCBI Official Synonym Symbols
Sudd; D18Ertd331e; 1200013N13Rik; E130306C24Rik
UniProt Protein Name
Serine/threonine-protein kinase RIO3
UniProt Synonym Protein Names
RIO kinase 3
UniProt Gene Name
Riok3
NCBI Protein Information
serine/threonine-protein kinase RIO3

UniProt Comments for Riok3

Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3. Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling. Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway. May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA.
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Research Articles on Riok3

1. down-regulation of miR-191 is essential for erythroid chromatin condensation and enucleation by allowing up-regulation of Riok3 and Mxi1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Riok3 recombinant protein

 Reference Product  PubMed Publications
 Riok2 recombinant protein  >1 publications with Riok3 and Riok2

Diseases associated with Riok3 recombinant protein

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >2 publications with Riok3 and Adenocarcinoma
 Lung Neoplasms Antibodies  >1 publications with Riok3 and Lung Neoplasms
 Prostatic Diseases Antibodies  >1 publications with Riok3 and Prostatic Diseases
 Necrosis Antibodies  >1 publications with Riok3 and Necrosis

Organs/Tissues associated with Riok3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >1 publications with Riok3 and Prostate
 Lung Antibodies  >1 publications with Riok3 and Lung
 Kidney Antibodies  >1 publications with Riok3 and Kidney
 Pancreas Antibodies  >1 publications with Riok3 and Pancreas
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