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C-C Motif Chemokine 27 (CCL27) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1313548

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines.… More details

$710 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-C motif chemokine 27 (CCL27), Recombinant Protein
Full Product Name
Recombinant Human C-C motif chemokine 27 (CCL27)
Product Gene Name
CCL27 recombinant protein
Product Synonym Gene Name
CCL27
Sequence
FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
12,618 Da
Sequence Positions
25-112, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
604833
3D Structure
ModBase 3D Structure for Q9Y4X3
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CCL27 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL27 purchase

MBS1313548 is a recombinant protein targeting CCL27. Also known as Recombinant Human C-C motif chemokine 27 (CCL27). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL27. It may not necessarily be applicable to this product.

NCBI GI #
5730035
NCBI GeneID
10850
NCBI Accession #
NP_006655.1
UniProt Primary Accession #
Q9Y4X3
UniProt Related Accession #
Q9Y4X3
GenBank Nucleotide #
NM_006664.3
NCBI Official Full Name
C-C motif chemokine 27
NCBI Official Synonym Full Names
C-C motif chemokine ligand 27
NCBI Official Symbol
CCL27
NCBI Official Synonym Symbols
ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27
UniProt Protein Name
C-C motif chemokine 27
UniProt Synonym Protein Names
CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27
Protein Family
C-C motif chemokine
UniProt Gene Name
CCL27
UniProt Synonym Gene Names
ILC; SCYA27; CTACK
NCBI Protein Information
C-C motif chemokine 27

NCBI Summary for CCL27

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]
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UniProt Comments for CCL27

Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.

Research Articles on CCL27

1. CCR10/CCL27 crosstalk mediated drug resistance, contributing to failure of proteasome-inhibitors in multiple myeloma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CCL27 recombinant protein

 Reference Product  PubMed Publications
 CCR10 recombinant protein  >60 publications with CCL27 and CCR10
 CCL20 recombinant protein  >21 publications with CCL27 and CCL20
 CXCL10 recombinant protein  >20 publications with CCL27 and CXCL10
 CCR7 recombinant protein  >15 publications with CCL27 and CCR7
 CCL21 recombinant protein  >14 publications with CCL27 and CCL21
 CCR6 recombinant protein  >5 publications with CCL27 and CCR6
 CCR5 recombinant protein  >5 publications with CCL27 and CCR5
 CCL25 recombinant protein  >5 publications with CCL27 and CCL25
 CCBP2 recombinant protein  >4 publications with CCL27 and CCBP2
 CXCR5 recombinant protein  >1 publications with CCL27 and CXCR5

Pathways associated with CCL27 recombinant protein

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with CCL27 recombinant protein

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >55 publications with CCL27 and Immune System Diseases
 Necrosis Antibodies  >33 publications with CCL27 and Necrosis
 Skin Neoplasms Antibodies  >16 publications with CCL27 and Skin Neoplasms
 Disease Models, Animal Antibodies  >11 publications with CCL27 and Disease Models, Animal
 Dermatitis, Allergic Contact Antibodies  >11 publications with CCL27 and Dermatitis, Allergic Contact
 Drug-Related Side Effects and Adverse Reactions Antibodies  >6 publications with CCL27 and Drug-Related Side Effects and Adverse Reactions
 Nervous System Diseases Antibodies  >5 publications with CCL27 and Nervous System Diseases
 Liver Diseases Antibodies  >3 publications with CCL27 and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with CCL27 and Liver Neoplasms
 Precancerous Conditions Antibodies  >2 publications with CCL27 and Precancerous Conditions

Organs/Tissues associated with CCL27 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >6 publications with CCL27 and Lung
 Connective Tissue Antibodies  >4 publications with CCL27 and Connective Tissue
 Eye Antibodies  >2 publications with CCL27 and Eye
 Testis Antibodies  >2 publications with CCL27 and Testis
 Placenta Antibodies  >2 publications with CCL27 and Placenta
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