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Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Delta Isoform (PPP2R2D) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1313653

MBS1313653 is a recombinant protein targeting PPP2R2D. Also known as Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1225 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D), Recombinant Protein
Full Product Name
Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D)
Product Gene Name
PPP2R2D recombinant protein
Product Synonym Gene Name
PPP2R2D
Sequence
MAGAGGGGCP AGGNDFQWCF SQVKGAIDED VAEADIISTV EFNYSGDLLA TGDKGGRVVI FQREQENKSR PHSRGEYNVY STFQSHEPEF DYLKSLEIEE KINKIRWLPQ QNAAHFLLST NDKTIKLWKI SERDKRAEGY NLKDEDGRLR DPFRITALRV PILKPMDLMV EASPRRIFAN AHTYHINSIS VNSDHETYLS ADDLRINLWH LEITDRSFNI VDIKPANMEE LTEVITAAEF HPHQCNVFVY SSSKGTIRLC DMRSSALCDR HSKFFEEPED PSSRSFFSEI ISSISDVKFS HSGRYMMTRD YLSVKVWDLN MESRPVETHQ VHEYLRSKLC SLYENDCIFD KFECCWNGSD SAIMTGSYNN FFRMFDRDTR RDVTLEASRE SSKPRASLKP RKVCTGGKRR KDEISVDSLD FNKKILHTAW HPVDNVIAVA ATNNLYIFQD KIN
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
52,042 Da
Sequence Positions
1-453, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
613992
3D Structure
ModBase 3D Structure for Q66LE6
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PPP2R2D recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP2R2D. It may not necessarily be applicable to this product.

NCBI GI #
604723314
NCBI GeneID
55844
NCBI Accession #
NP_001278239.1
UniProt Primary Accession #
Q66LE6
UniProt Secondary Accession #
Q5SQJ2; Q9P1Y7; A8KAK0
UniProt Related Accession #
Q66LE6
GenBank Nucleotide #
NM_001291310.1
NCBI Official Full Name
serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform b
NCBI Official Synonym Full Names
protein phosphatase 2 regulatory subunit Bdelta
NCBI Official Symbol
PPP2R2D
NCBI Official Synonym Symbols
B55D; MDS026; B55delta
UniProt Protein Name
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
UniProt Synonym Protein Names
PP2A subunit B isoform B55-delta; PP2A subunit B isoform PR55-delta; PP2A subunit B isoform R2-delta; PP2A subunit B isoform delta
Protein Family
Serine/threonine-protein phosphatase
UniProt Gene Name
PPP2R2D
UniProt Synonym Gene Names
KIAA1541
NCBI Protein Information
serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

UniProt Comments for PPP2R2D

B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment ().
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Research Articles on PPP2R2D

1. The PP2A regulatory subunit PPP2R2D inhibits T-cell proliferation and survival within tumors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PPP2R2D recombinant protein

 Reference Product  PubMed Publications
 PPP2CB recombinant protein  >5 publications with PPP2R2D and PPP2CB
 PPP2CA recombinant protein  >5 publications with PPP2R2D and PPP2CA
 PPP2R2A recombinant protein  >2 publications with PPP2R2D and PPP2R2A

Pathways associated with PPP2R2D recombinant protein

 Products by Pathway  Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram

Diseases associated with PPP2R2D recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with PPP2R2D and Inflammation
 Disease Models, Animal Antibodies  >1 publications with PPP2R2D and Disease Models, Animal

Organs/Tissues associated with PPP2R2D recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with PPP2R2D and Lung
 Blood Antibodies  >1 publications with PPP2R2D and Blood
 Embryonic Tissue Antibodies  >1 publications with PPP2R2D and Embryonic Tissue
 Brain Antibodies  >1 publications with PPP2R2D and Brain
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