• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MOB Kinase Activator 1a (MOB1A) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1314185

MBS1314185 is a recombinant protein targeting Mob1a. Also known as Recombinant Mouse MOB kinase activator 1A (Mob1a). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$870 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MOB kinase activator 1A (Mob1a), Recombinant Protein
Full Product Name
Recombinant Mouse MOB kinase activator 1A (Mob1a)
Product Gene Name
Mob1a recombinant protein
Product Synonym Gene Name
Mob1a
Sequence
SFLFSSRSSK TFKPKKNIPE GSHQYELLKH AEATLGSGNL RQAVMLPEGE DLNEWIAVNT VDFFNQINML YGTITEFCTE ASCPVMSAGP RYEYHWADGT NIKKPIKCSA PKYIDYLMTW VQDQLDDETL FPSKIGVPFP KNFMSVAKTI LKRLFRVYAH IYHQHFDSVM QLQEEAHLNT SFKHFIFFVQ EFNLIDRREL APLQELIEKL GSKDR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
16,336 Da
Sequence Positions
2-216, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q921Y0
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mob1a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Mob1a. It may not necessarily be applicable to this product.

NCBI GI #
21704148
NCBI GeneID
232157
NCBI Accession #
NP_663546.1
UniProt Primary Accession #
Q921Y0
UniProt Secondary Accession #
Q3TJA6; Q8C194; Q8C1C7
UniProt Related Accession #
Q921Y0
GenBank Nucleotide #
NM_145571.2
NCBI Official Full Name
MOB kinase activator 1A
NCBI Official Synonym Full Names
MOB kinase activator 1A
NCBI Official Symbol
Mob1a
NCBI Official Synonym Symbols
MOB1; MOB4B; Mobk1b; Mobkl1b; 4022402H07Rik
UniProt Protein Name
MOB kinase activator 1A
UniProt Synonym Protein Names
Mob1 homolog 1B; Mps one binder kinase activator-like 1B
Protein Family
MOB kinase activator
UniProt Gene Name
Mob1a
UniProt Synonym Gene Names
Mobk1b; Mobkl1b
NCBI Protein Information
MOB kinase activator 1A

UniProt Comments for Mob1a

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38 ().
Show more

Research Articles on Mob1a

1. MOB1A and MOB1B have overlapping functions in skin homeostasis, and exert their roles as tumor suppressors by regulating downstream elements of the Hippo pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Mob1a recombinant protein

 Products by Pathway  Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Hippo Pathway antibodies  Signaling By Hippo Pathway Diagram

Diseases associated with Mob1a recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with Mob1a and Neoplasms
 Intestinal Neoplasms Antibodies  >1 publications with Mob1a and Intestinal Neoplasms
 Liver Neoplasms Antibodies  >1 publications with Mob1a and Liver Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with Mob1a and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >1 publications with Mob1a and Neoplasm Metastasis

Organs/Tissues associated with Mob1a recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with Mob1a and Liver
 Kidney Antibodies  >1 publications with Mob1a and Kidney
 Lung Antibodies  >1 publications with Mob1a and Lung
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000