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Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH5 (ALKBH5) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1317862

MBS1317862 is a recombinant protein targeting Alkbh5. Also known as Recombinant Mouse Probable alpha-ketoglutarate-dependent dioxygenase ABH5 (Alkbh5). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1130 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Probable alpha-ketoglutarate-dependent dioxygenase ABH5 (Alkbh5), Recombinant Protein
Full Product Name
Recombinant Mouse Probable alpha-ketoglutarate-dependent dioxygenase ABH5 (Alkbh5)
Product Synonym Gene Name
Alkbh5
Sequence
AAASGYTDLR EKLKSMTSRD NYKAGSREAA AAAAAAVAAA AAAAAAAEPY PASGTTKRKY QEDSDPERSD YEEHQLQKEE EARKVKSGIR QIRLFSQDEC SKIEARIDEV VSRAEKGLYN EHTVDRAPLR NKYFFGEGYT YGAQLQKRGP GQERLYPPGD VDEIPDWVHQ LVIQKLVEHR VIPEGFVNSA VINDYQPGGC IVSHVDPIHI FERPIVSVSF FSDSALCFGC KFQFKPIRVS EPVLSLPVRR GSVTVLSGYA ADEITHCIRP QDIKERRAVI ILRKTRLDAP RLETKSLSSS TLPPSYASDR LSGNTRDPAL KPKRSHRKAD PDAAHRPRIL EMDKEENRRS VLLPTHRRRG SFSSENYWRK SYESSEDCPE AASSPTRKVK MRRH
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
44,411 Da
Sequence Positions
2-395, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q3TSG4
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Alkbh5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Alkbh5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
RNA demethylase ALKBH5
NCBI Official Synonym Full Names
alkB homolog 5, RNA demethylase
NCBI Official Symbol
Alkbh5
NCBI Official Synonym Symbols
Abh5; Ofoxd; AW050020; AW215868; E130207K11
UniProt Protein Name
RNA demethylase ALKBH5
UniProt Synonym Protein Names
Alkylated DNA repair protein alkB homolog 5; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5
Protein Family
UniProt Gene Name
Alkbh5
UniProt Synonym Gene Names
Abh5; Ofoxd
NCBI Protein Information
RNA demethylase ALKBH5

UniProt Comments for Alkbh5

Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (). Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export (). Required for spermatogenesis (PubMed:23177736).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Alkbh5 recombinant protein

Organs/Tissues associated with Alkbh5 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >1 publications with Alkbh5 and Testis
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