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Dnaj Homolog Subfamily B Member 1 (DNAJB1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1319188

MBS1319188 is a recombinant protein targeting Dnajb1. Also known as Recombinant Mouse DnaJ homolog subfamily B member 1 (Dnajb1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1055 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DnaJ homolog subfamily B member 1 (Dnajb1), Recombinant Protein
Full Product Name
Recombinant Mouse DnaJ homolog subfamily B member 1 (Dnajb1)
Product Gene Name
Dnajb1 recombinant protein
Product Synonym Gene Name
Dnajb1
Sequence
GKDYYQTLGL ARGASDDEIK RAYRRQALRY HPDKNKEPGA EEKFKEIAEA YDVLSDPRKR EIFDRYGEEG LKGGSPSGGS SGGANGTSFS YTFHGDPHAM FAEFFGGRNP FDTFFGQRNG EEGMDIDDTF SSFPMGMGGF TNMNFGRSRP SQEPTRKKQD PPVTHDLRVS LEEIYSGCTK KMKISHKRLN PDGKSIRNED KILTIEVKRG WKEGTKITFP KEGDQTSNNI PADIVFVLKD KPHNIFKRDG SDVIYPARIS LREALCGCTV NVPTLDGRTI PVVFKDVIRP GMRRKVPGEG LPLPKTPEKR GDLVIEFEVI FPERIPVSSR TILEQVLPI
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
38,167 Da
Sequence Positions
2-340, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9QYJ3
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Dnajb1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Dnajb1. It may not necessarily be applicable to this product.

NCBI GI #
9055242
NCBI GeneID
81489
NCBI Accession #
NP_061278.1
UniProt Primary Accession #
Q9QYJ3
UniProt Related Accession #
Q9QYJ3
GenBank Nucleotide #
NM_018808.3
NCBI Official Full Name
dnaJ homolog subfamily B member 1 isoform 1
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member B1
NCBI Official Symbol
Dnajb1
NCBI Official Synonym Symbols
DjB1; Hdj1; HSPF1; Hsp40; 0610007I11Rik
UniProt Protein Name
DnaJ homolog subfamily B member 1
UniProt Synonym Protein Names
Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40
Protein Family
DnaJ homolog subfamily
UniProt Gene Name
Dnajb1
UniProt Synonym Gene Names
Hsp40; Hspf1; HSP40; Heat shock protein 40
NCBI Protein Information
dnaJ homolog subfamily B member 1

NCBI Summary for Dnajb1

This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. The encoded protein may also inhibit apoptosis. Peritoneal macrophages derived from homozygous knockout mice for this gene exhibit impaired heat tolerance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
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UniProt Comments for Dnajb1

Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
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Research Articles on Dnajb1

1. Generation of the Dnajb1-Prkaca fusion gene in wild-type mice to be sufficient to initiate formation of tumors that have many features of human fibrolamellar hepatocellular carcinonma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Dnajb1 recombinant protein

 Reference Product  PubMed Publications
 Hspa1a recombinant protein  >23 publications with Dnajb1 and Hspa1a
 Hspa8 recombinant protein  >23 publications with Dnajb1 and Hspa8
 Hsf1 recombinant protein  >10 publications with Dnajb1 and Hsf1
 Hsph1 recombinant protein  >8 publications with Dnajb1 and Hsph1
 Hspa1b recombinant protein  >6 publications with Dnajb1 and Hspa1b
 Hspa2 recombinant protein  >3 publications with Dnajb1 and Hspa2
 Hsp90aa1 recombinant protein  >3 publications with Dnajb1 and Hsp90aa1
 Hspa4 recombinant protein  >1 publications with Dnajb1 and Hspa4
 Hsp90ab1 recombinant protein  >1 publications with Dnajb1 and Hsp90ab1

Pathways associated with Dnajb1 recombinant protein

 Products by Pathway  Pathway Diagram
 Attenuation Phase Pathway antibodies  Attenuation Phase Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 HSF1-dependent Transactivation Pathway antibodies  HSF1-dependent Transactivation Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 MAPK Family Signaling Cascades Pathway antibodies  MAPK Family Signaling Cascades Pathway Diagram
 MAPK6/MAPK4 Signaling Pathway antibodies  MAPK6/MAPK4 Signaling Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram

Diseases associated with Dnajb1 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >17 publications with Dnajb1 and Nervous System Diseases
 Carcinoma, Hepatocellular Antibodies  >11 publications with Dnajb1 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >10 publications with Dnajb1 and Liver Diseases
 Disease Models, Animal Antibodies  >8 publications with Dnajb1 and Disease Models, Animal
 Liver Neoplasms Antibodies  >8 publications with Dnajb1 and Liver Neoplasms
 Inflammation Antibodies  >8 publications with Dnajb1 and Inflammation
 Lung Diseases Antibodies  >7 publications with Dnajb1 and Lung Diseases
 Cardiovascular Diseases Antibodies  >4 publications with Dnajb1 and Cardiovascular Diseases
 Fibrosis Antibodies  >4 publications with Dnajb1 and Fibrosis
 Chromosome Aberrations Antibodies  >3 publications with Dnajb1 and Chromosome Aberrations

Organs/Tissues associated with Dnajb1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >22 publications with Dnajb1 and Brain
 Liver Antibodies  >18 publications with Dnajb1 and Liver
 Blood Antibodies  >15 publications with Dnajb1 and Blood
 Lung Antibodies  >6 publications with Dnajb1 and Lung
 Testis Antibodies  >5 publications with Dnajb1 and Testis
 Heart Antibodies  >5 publications with Dnajb1 and Heart
 Eye Antibodies  >4 publications with Dnajb1 and Eye
 Muscle Antibodies  >4 publications with Dnajb1 and Muscle
 Pancreas Antibodies  >3 publications with Dnajb1 and Pancreas
 Lymph Node Antibodies  >3 publications with Dnajb1 and Lymph Node
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