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Polyadenylate-Binding Protein-Interacting Protein 1 (PAIP1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1324265

This protein interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at… More details

$1135 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Polyadenylate-binding protein-interacting protein 1 (Paip1), Recombinant Protein
Full Product Name
Recombinant Mouse Polyadenylate-binding protein-interacting protein 1 (Paip1)
Product Gene Name
Paip1 recombinant protein
Product Synonym Gene Name
Paip1
Sequence
MSDSFDRAPE QTKPQRAPPS SQDKIPQQNS ESAMAKPQVV VAPVLMSKLS ANAPEFYPSG YSSNYTESYE DGCEDYPTLS EYVQDFLNHL TEQPGSFETE IEQFAETLNG WVTTDDALQE LVELIYQQAT SIPNFSYMGA RLCNYLSHHL TISPQSGNFR QLLLQRCRTE YEAKDQAAKG DEVTRKRFHA FVLFLGELYL NLEIKGTNGQ VTRADILQVG LRELLNALFS NPMDDNLICA VKLLKLTGSV LEDTWKEKGK TDMEEIIQRI ENVVLDANCS RDVKQMLLKL VELRSSNWGR VHATSTYREA TPENDPNYFM NEPTFYTSDG VPFTAADPDY QEKYQELLER EDFFPDYEEN GTDLSGAGDP YLDDIDDEMD PEIEEAYEKF CLESERKRKQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
45,702 Da
Sequence Positions
1-400, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8VE62
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Paip1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Paip1 purchase

MBS1324265 is a recombinant protein targeting Paip1. Also known as Recombinant Mouse Polyadenylate-binding protein-interacting protein 1 (Paip1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Paip1. It may not necessarily be applicable to this product.

NCBI GI #
21703908
NCBI GeneID
218693
NCBI Accession #
NP_663432.1
UniProt Primary Accession #
Q8VE62
UniProt Secondary Accession #
Q9WUC9
UniProt Related Accession #
Q8VE62
GenBank Nucleotide #
NM_145457.4
NCBI Official Full Name
polyadenylate-binding protein-interacting protein 1 isoform 1
NCBI Official Synonym Full Names
polyadenylate binding protein-interacting protein 1
NCBI Official Symbol
Paip1
NCBI Official Synonym Symbols
PAIP-1
UniProt Protein Name
Polyadenylate-binding protein-interacting protein 1
Protein Family
Polyadenylate-binding protein-interacting protein
UniProt Gene Name
Paip1
UniProt Synonym Gene Names
PABP-interacting protein 1; PAIP-1; Poly(A)-binding protein-interacting protein 1
NCBI Protein Information
polyadenylate-binding protein-interacting protein 1

UniProt Comments for Paip1

Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Paip1 recombinant protein

 Reference Product  PubMed Publications
 Eif4e recombinant protein  >7 publications with Paip1 and Eif4e
 Pabpc1 recombinant protein  >2 publications with Paip1 and Pabpc1
 Pabpc2 recombinant protein  >1 publications with Paip1 and Pabpc2
 Eif4g1 recombinant protein  >1 publications with Paip1 and Eif4g1

Pathways associated with Paip1 recombinant protein

 Products by Pathway  Pathway Diagram
 Deadenylation Of MRNA Pathway antibodies  Deadenylation Of MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 Translation Factors Pathway antibodies  Translation Factors Pathway Diagram

Diseases associated with Paip1 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with Paip1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >1 publications with Paip1 and Congenital Abnormalities
 Abnormalities, Multiple Antibodies  >1 publications with Paip1 and Abnormalities, Multiple
 Disease Models, Animal Antibodies  >1 publications with Paip1 and Disease Models, Animal
 Uterine Cervical Neoplasms Antibodies  >1 publications with Paip1 and Uterine Cervical Neoplasms

Organs/Tissues associated with Paip1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Spinal Cord Antibodies  >1 publications with Paip1 and Spinal Cord
 Uncharacterized Tissue Antibodies  >1 publications with Paip1 and Uncharacterized Tissue
 Muscle Antibodies  >1 publications with Paip1 and Muscle
 Brain Antibodies  >1 publications with Paip1 and Brain
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