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Rap Guanine Nucleotide Exchange Factor 1 (RAPGEF1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1324981

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis,… More details

$885 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Rap guanine nucleotide exchange factor 1 (RAPGEF1), Recombinant Protein
Full Product Name
Recombinant Human Rap guanine nucleotide exchange factor 1 (RAPGEF1) , partial
Product Synonym Gene Name
RAPGEF1
Sequence
HSHEIAEQLT LLDAELFYKI EIPEVLLWAK EQNEEKSPNL TQFTEHFNNM SYWVRSIIML QEKAQDRERL LLKFIKIMKH LRKLNNFNSY LAILSALDSA PIRRLEWQKQ TSEGLAEYCT LIDSSSSFRA YRAALSEVEP PCIPYLGLIL QDLTFVHLGN PDYIDGKVNF SKRWQQFNIL DSMRCFQQAH YDMRRNDDII NFFNDFSDHL AEEALWELSL KIKPR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
122,287 Da
Sequence Positions
840-1064aa; partial;
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
600303
3D Structure
ModBase 3D Structure for Q13905
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RAPGEF1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAPGEF1 purchase

MBS1324981 is a recombinant protein targeting RAPGEF1. Also known as Recombinant Human Rap guanine nucleotide exchange factor 1 (RAPGEF1) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for RAPGEF1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rap guanine nucleotide exchange factor 1 isoform c
NCBI Official Synonym Full Names
Rap guanine nucleotide exchange factor 1
NCBI Official Symbol
RAPGEF1
NCBI Official Synonym Symbols
C3G; GRF2
UniProt Protein Name
Rap guanine nucleotide exchange factor 1
UniProt Synonym Protein Names
CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3G
UniProt Gene Name
RAPGEF1
UniProt Synonym Gene Names
GRF2
NCBI Protein Information
rap guanine nucleotide exchange factor 1

UniProt Comments for RAPGEF1

Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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