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Exocyst Complex Component 2 (EXOC2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1325178

This protein is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the… More details

$1255 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Exocyst complex component 2 (EXOC2), Recombinant Protein
Full Product Name
Recombinant Human Exocyst complex component 2 (EXOC2) , partial
Product Gene Name
EXOC2 recombinant protein
Product Synonym Gene Name
EXOC2
Sequence
RQPPLVTGIS PNEGIPWTKV TIRGENLGTG PTDLIGLTIC GHNCLLTAEW MSASKIVCRV GQAKNDKGDI IVTTKSGGRG TSTVSFKLLK PEKIGILDQS AVWVDEMNYY DMRTDRNKGI PPLSLRPANP LGIEIEKSKF SQKDLEMLFH GMSADFTSEN FSAAWYLIEN HSNTSFEQLK MAVTNLKRQA NKKSEGSLAY VKGGLSTFFE AQDALSAIHQ KLEADGTEKV EGSMTQKLEN VLNRASNTAD TLFQEVLGRK DKADSTRNAL NVLQRFKFLF NLPLNIERNI QKGDYDVVIN DYEKAKSLFG KTEVQVFKKY YAEVETRIEA LRELLLDKLL ETPSTLHDQK RYIRYLSDLH ASGDPAWQCI GAQHKWILQL MHSCKEGYVK DLKGNPGLHS PMLDLDNDTR PSVLGHLSQT ASLKRGSSFQ SGRDDTWRYK TPHRVAFVEK LTKLVLSQLP NFWKLWISYV NGSLFS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
104,066 Da
Sequence Positions
5-480aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
615329
3D Structure
ModBase 3D Structure for Q96KP1
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EXOC2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EXOC2 purchase

MBS1325178 is a recombinant protein targeting EXOC2. Also known as Recombinant Human Exocyst complex component 2 (EXOC2) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for EXOC2. It may not necessarily be applicable to this product.

NCBI GI #
21361625
NCBI GeneID
55770
NCBI Accession #
NP_060773.3
UniProt Primary Accession #
Q96KP1
UniProt Secondary Accession #
Q5JPC8; Q96AN6; Q9NUZ8; Q9UJM7; B2RBE6
UniProt Related Accession #
Q96KP1
GenBank Nucleotide #
NM_018303.5
NCBI Official Full Name
exocyst complex component 2
NCBI Official Synonym Full Names
exocyst complex component 2
NCBI Official Symbol
EXOC2
NCBI Official Synonym Symbols
SEC5; Sec5p; SEC5L1
UniProt Protein Name
Exocyst complex component 2
UniProt Synonym Protein Names
Exocyst complex component Sec5
Protein Family
Exocyst complex component
UniProt Gene Name
EXOC2
UniProt Synonym Gene Names
SEC5; SEC5L1
NCBI Protein Information
exocyst complex component 2

NCBI Summary for EXOC2

The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
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UniProt Comments for EXOC2

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

Research Articles on EXOC2

1. data suggest that the induction of SGK1 through treatment with dexamethasone alters MT dynamics to increase Sec5-GEF-H1 interactions, which promote GEF-H1 targeting to adhesion sites.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EXOC2 recombinant protein

 Reference Product  PubMed Publications
 RALA recombinant protein  >9 publications with EXOC2 and RALA
 EXOC8 recombinant protein  >4 publications with EXOC2 and EXOC8
 EXOC3 recombinant protein  >1 publications with EXOC2 and EXOC3

Pathways associated with EXOC2 recombinant protein

 Products by Pathway  Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Diabetes Pathways antibodies  Diabetes Pathways Diagram
 Insulin Pathway antibodies  Insulin Pathway Diagram
 Insulin Synthesis And Processing Pathway antibodies  Insulin Synthesis And Processing Pathway Diagram

Diseases associated with EXOC2 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7 publications with EXOC2 and Neoplasms
 Carcinoma, Squamous Cell Antibodies  >2 publications with EXOC2 and Carcinoma, Squamous Cell
 Skin Neoplasms Antibodies  >2 publications with EXOC2 and Skin Neoplasms
 Lung Neoplasms Antibodies  >1 publications with EXOC2 and Lung Neoplasms
 Prostatic Neoplasms Antibodies  >1 publications with EXOC2 and Prostatic Neoplasms
 Urologic Neoplasms Antibodies  >1 publications with EXOC2 and Urologic Neoplasms
 Urinary Bladder Neoplasms Antibodies  >1 publications with EXOC2 and Urinary Bladder Neoplasms

Organs/Tissues associated with EXOC2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >3 publications with EXOC2 and Skin
 Eye Antibodies  >2 publications with EXOC2 and Eye
 Blood Antibodies  >2 publications with EXOC2 and Blood
 Bone Antibodies  >1 publications with EXOC2 and Bone
 Prostate Antibodies  >1 publications with EXOC2 and Prostate
 Lung Antibodies  >1 publications with EXOC2 and Lung
 Embryonic Tissue Antibodies  >1 publications with EXOC2 and Embryonic Tissue
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