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Attractin (ATRN) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1325196

Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other isoform is a secreted… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Attractin (Atrn), Recombinant Protein
Full Product Name
Recombinant Mouse Attractin (Atrn) , partial
Product Gene Name
Atrn recombinant protein
Product Synonym Gene Name
Atrn
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
158,058 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9WU60
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Atrn recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Atrn purchase

MBS1325196 is a recombinant protein targeting Atrn. Also known as Recombinant Mouse Attractin (Atrn) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Atrn. It may not necessarily be applicable to this product.

NCBI GI #
87299635
NCBI GeneID
11990
NCBI Accession #
NP_033860.2
UniProt Primary Accession #
Q9WU60
UniProt Secondary Accession #
Q9R263; Q9WU77; A2AP43
UniProt Related Accession #
Q9WU60
GenBank Nucleotide #
NM_009730.3
NCBI Official Full Name
attractin preproprotein
NCBI Official Synonym Full Names
attractin
NCBI Official Symbol
Atrn
NCBI Official Synonym Symbols
mg; Mgca; AW558010
UniProt Protein Name
Attractin
UniProt Synonym Protein Names
Protein mahogany
UniProt Gene Name
Atrn
UniProt Synonym Gene Names
Mg; Mgca
NCBI Protein Information
attractin

NCBI Summary for Atrn

This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
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UniProt Comments for Atrn

Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines (). May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system ().
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Research Articles on Atrn

1. Data indicate that Attractin was involved in male reproduction in both human and BALB/c mice, but it exerted a different expression profile in different species.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Atrn recombinant protein

 Disease Name  Pubmed Publications
 Obesity Antibodies  >17 publications with Atrn and Obesity
 Brain Diseases Antibodies  >7 publications with Atrn and Brain Diseases
 Neurodegenerative Diseases Antibodies  >6 publications with Atrn and Neurodegenerative Diseases
 Disease Models, Animal Antibodies  >3 publications with Atrn and Disease Models, Animal
 Nerve Degeneration Antibodies  >3 publications with Atrn and Nerve Degeneration
 Melanoma Antibodies  >3 publications with Atrn and Melanoma
 Carcinoma, Squamous Cell Antibodies  >2 publications with Atrn and Carcinoma, Squamous Cell
 Seizures Antibodies  >2 publications with Atrn and Seizures
 Weight Gain Antibodies  >2 publications with Atrn and Weight Gain
 Diabetes Mellitus, Type 2 Antibodies  >1 publications with Atrn and Diabetes Mellitus, Type 2

Organs/Tissues associated with Atrn recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >20 publications with Atrn and Brain
 Skin Antibodies  >9 publications with Atrn and Skin
 Spinal Cord Antibodies  >7 publications with Atrn and Spinal Cord
 Testis Antibodies  >4 publications with Atrn and Testis
 Bone Antibodies  >1 publications with Atrn and Bone
 Eye Antibodies  >1 publications with Atrn and Eye
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