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Aconitate Hydratase, Mitochondrial (ACO2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1325757

This protein belongs to the aconitaseIPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the… More details

$1615 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Aconitate hydratase, mitochondrial (Aco2), Recombinant Protein
Full Product Name
Recombinant Mouse Aconitate hydratase, mitochondrial (Aco2)
Product Gene Name
Aco2 recombinant protein
Product Synonym Gene Name
Aco2
Sequence
QRAKVAMSHF EPSEYIRYDL LEKNINIVRK RLNRPLTLSE KIVYGHLDDP ANQEIERGKT YLRLRPDRVA MQDATAQMAM LQFISSGLPK VAVPSTIHCD HLIEAQVGGE KDLRRAKDIN QEVYNFLATA GAKYGVGFWR PGSGIIHQII LENYAYPGVL LIGTDSHTPN GGGLGGICIG VGGADAVDVM AGIPWELKCP KVIGVKLTGS LSGWTSPKDV ILKVAGILTV KGGTGAIVEY HGPGVDSISC TGMATICNMG AEIGATTSVF PYNHRMKKYL SKTGRTDIAN LAEEFKDHLV PDPGCQYDQV IEINLNELKP HINGPFTPDL AHPVADVGTV AEKEGWPLDI RVGLIGSCTN SSYEDMGRSA AVAKQALAHG LKCKSQFTIT PGSEQIRATI ERDGYAQILR DVGGIVLANA CGPCIGQWDR KDIKKGEKNT IVTSYNRNFT GRNDANPETH AFVTSPEIVT ALAIAGTLKF NPETDFLTGK DGKKFKLEAP DADELPRSDF DPGQDTYQHP PKDSSGQRVD VSPTSQRLQL LEPFDKWDGK DLEDLQILIK VKGKCTTDHI SAAGPWLKFR GHLDNISNNL LIGAINIENG KANSVRNAVT QEFGPVPDTA RYYKKHGIRW VVIGDENYGE GSSREHAALE PRHLGGRAII TKSFARIHET NLKKQGLLPL TFADPSDYNK IHPVDKLTIQ GLKDFAPGKP LKCVIKHPNG TQETILLNHT FNETQIEWFR AGSALNRMKE LQQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
85,464 Da
Sequence Positions
28-780, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q99KI0
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Aco2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Aco2 purchase

MBS1325757 is a recombinant protein targeting Aco2. Also known as Recombinant Mouse Aconitate hydratase, mitochondrial (Aco2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Aco2. It may not necessarily be applicable to this product.

NCBI GI #
18079339
NCBI GeneID
11429
NCBI Accession #
NP_542364.1
UniProt Primary Accession #
Q99KI0
UniProt Secondary Accession #
Q3UDK9; Q3ULG9; Q3UNH7; Q505P4
UniProt Related Accession #
Q99KI0
GenBank Nucleotide #
NM_080633.2
NCBI Official Full Name
aconitate hydratase, mitochondrial
NCBI Official Synonym Full Names
aconitase 2, mitochondrial
NCBI Official Symbol
Aco2
NCBI Official Synonym Symbols
Aco3; Aco-2; D10Wsu183e
UniProt Protein Name
Aconitate hydratase, mitochondrial
UniProt Synonym Protein Names
Citrate hydro-lyase
Protein Family
1-aminocyclopropane-1-carboxylate oxidase
UniProt Gene Name
Aco2
UniProt Synonym Gene Names
Aconitase
NCBI Protein Information
aconitate hydratase, mitochondrial

UniProt Comments for Aco2

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

Research Articles on Aco2

1. Activation of mitochondrial aconitase is acetylation-dependent.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Aco2 recombinant protein

 Products by Pathway  Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 Amino Acid Metabolism Pathway antibodies  Amino Acid Metabolism Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram

Diseases associated with Aco2 recombinant protein

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >12 publications with Aco2 and Lung Diseases
 Nervous System Diseases Antibodies  >10 publications with Aco2 and Nervous System Diseases
 Brain Diseases Antibodies  >8 publications with Aco2 and Brain Diseases
 Cardiovascular Diseases Antibodies  >8 publications with Aco2 and Cardiovascular Diseases
 Heart Diseases Antibodies  >5 publications with Aco2 and Heart Diseases
 Inflammation Antibodies  >5 publications with Aco2 and Inflammation
 Fibrosis Antibodies  >5 publications with Aco2 and Fibrosis
 Ischemia Antibodies  >4 publications with Aco2 and Ischemia
 Heart Failure Antibodies  >4 publications with Aco2 and Heart Failure
 Disease Models, Animal Antibodies  >4 publications with Aco2 and Disease Models, Animal

Organs/Tissues associated with Aco2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >39 publications with Aco2 and Blood
 Heart Antibodies  >17 publications with Aco2 and Heart
 Lung Antibodies  >16 publications with Aco2 and Lung
 Artery Antibodies  >13 publications with Aco2 and Artery
 Brain Antibodies  >10 publications with Aco2 and Brain
 Liver Antibodies  >6 publications with Aco2 and Liver
 Muscle Antibodies  >6 publications with Aco2 and Muscle
 Stomach Antibodies  >6 publications with Aco2 and Stomach
 Kidney Antibodies  >4 publications with Aco2 and Kidney
 Prostate Antibodies  >4 publications with Aco2 and Prostate
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