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Cdc42-Interacting Protein 4 (TRIP10) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1327054

MBS1327054 is a recombinant protein targeting Trip10. Also known as Recombinant Mouse Cdc42-interacting protein 4 (Trip10). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1400 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cdc42-interacting protein 4 (Trip10), Recombinant Protein
Full Product Name
Recombinant Mouse Cdc42-interacting protein 4 (Trip10)
Product Gene Name
Trip10 recombinant protein
Product Synonym Gene Name
Trip10
Sequence
MDWGTELWDQ FEVLERHTQW GLDLLDKYVK FVKERAEVEQ AYAKQLRSLV KKYLPKRPTK DDPEVKFSQQ QSFVQLLQEV NDFAGQRELV AESLGIRVCL ELAKYSQEMK QERKMHFQEG RRAQQQLENG FKQLENSKRK FERDCREAEK AAHTAERLDQ DINATKADVE KAKQQAHLRN HMAEESKNEY AAQLQRFNRD QAHFYFSQMP QIFDKLQDMD ERRATRLGAG YGLLSEAELQ VVPIIGKCLE GMKVAAESVD AKNDSQVLIE LHKSGFARPG DLEFEDFSQV INRVPSDSSL GTPDGRPELR AASSRSRAKR WPFGKKNKPR PPSLSLLGGH LPSTLSDGPS SPRSGRDPLA ILSEISKSVK PRLASFRSFR GGRGTVATED FSHLPPEQQR KRLQQQLEER NRELQKEEDQ REALKKMKDV YEKTPQMGDP ASLEPRIAET LGNIERLKLE VQKYEAWLAE AESRVLSNRG DSLSRHARPP DPPTTAPPDS SSSSTNSGSQ DNKESSSEEP PSEGQDTPIY TEFDEDFEEP ASPIGQCVAI YHFEGSSEGT VSMSEGEDLS LMEEDKGDGW TRVRRKQGAE GYVPTSYLRV TLN
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
62,567 Da
Sequence Positions
1-603, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8CJ53
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Trip10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Trip10. It may not necessarily be applicable to this product.

NCBI GI #
334724448
NCBI GeneID
106628
NCBI Accession #
NP_001229318.1
UniProt Primary Accession #
Q8CJ53
UniProt Secondary Accession #
Q8BTR8; Q8R433; Q99LI0
UniProt Related Accession #
Q8CJ53
GenBank Nucleotide #
NM_001242389.1
NCBI Official Full Name
cdc42-interacting protein 4 isoform 1
NCBI Official Synonym Full Names
thyroid hormone receptor interactor 10
NCBI Official Symbol
Trip10
NCBI Official Synonym Symbols
Cip4; AI646975
UniProt Protein Name
Cdc42-interacting protein 4
UniProt Synonym Protein Names
Thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
Protein Family
Cdc42-interacting protein
UniProt Gene Name
Trip10
UniProt Synonym Gene Names
Cip4; TR-interacting protein 10; TRIP-10
NCBI Protein Information
cdc42-interacting protein 4

UniProt Comments for Trip10

Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL (). Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling.
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Research Articles on Trip10

1. CIP4 silencing can efficiently alleviate Streptozotocin-induced pulmonary fibrosis in mice, perhaps through suppressing Wnt/GSK-3beta/beta-catenin signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Trip10 recombinant protein

 Products by Pathway  Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram

Diseases associated with Trip10 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with Trip10 and Neoplasms
 Hypertension Antibodies  >3 publications with Trip10 and Hypertension
 Kidney Neoplasms Antibodies  >2 publications with Trip10 and Kidney Neoplasms
 Nervous System Diseases Antibodies  >2 publications with Trip10 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with Trip10 and Brain Diseases
 Movement Disorders Antibodies  >1 publications with Trip10 and Movement Disorders
 Blood Coagulation Disorders Antibodies  >1 publications with Trip10 and Blood Coagulation Disorders
 Hypertension, Renal Antibodies  >1 publications with Trip10 and Hypertension, Renal
 Liver Neoplasms Antibodies  >1 publications with Trip10 and Liver Neoplasms
 Disease Models, Animal Antibodies  >1 publications with Trip10 and Disease Models, Animal

Organs/Tissues associated with Trip10 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >4 publications with Trip10 and Kidney
 Brain Antibodies  >4 publications with Trip10 and Brain
 Skin Antibodies  >1 publications with Trip10 and Skin
 Bone Marrow Antibodies  >1 publications with Trip10 and Bone Marrow
 Heart Antibodies  >1 publications with Trip10 and Heart
 Uncharacterized Tissue Antibodies  >1 publications with Trip10 and Uncharacterized Tissue
 Bone Antibodies  >1 publications with Trip10 and Bone
 Liver Antibodies  >1 publications with Trip10 and Liver
 Lung Antibodies  >1 publications with Trip10 and Lung
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