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DNA Repair and Recombination Protein RAD54-Like (RAD54L) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1327983

MBS1327983 is a recombinant protein targeting RAD54L. Also known as Recombinant Human DNA repair and recombination protein RAD54-like (RAD54L). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1610 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNA repair and recombination protein RAD54-like (RAD54L), Recombinant Protein
Full Product Name
Recombinant Human DNA repair and recombination protein RAD54-like (RAD54L)
Product Gene Name
RAD54L recombinant protein
Product Synonym Gene Name
RAD54L
Sequence
MRRSLAPSQL AKRKPEGRSC DDEDWQPGLV TPRKRKSSSE TQIQECFLSP FRKPLSQLTN QPPCLDSSQH EAFIRSILSK PFKVPIPNYQ GPLGSRALGL KRAGVRRALH DPLEKDALVL YEPPPLSAHD QLKLDKEKLP VHVVVDPILS KVLRPHQREG VKFLWECVTS RRIPGSHGCI MADEMGLGKT LQCITLMWTL LRQSPECKPE IDKAVVVSPS SLVKNWYNEV GKWLGGRIQP LAIDGGSKDE IDQKLEGFMN QRGARVSSPI LIISYETFRL HVGVLQKGSV GLVICDEGHR LKNSENQTYQ ALDSLNTSRR VLISGTPIQN DLLEYFSLVH FVNSGILGTA HEFKKHFELP ILKGRDAAAS EADRQLGEER LRELTSIVNR CLIRRTSDIL SKYLPVKIEQ VVCCRLTPLQ TELYKRFLRQ AKPAEELLEG KMSVSSLSSI TSLKKLCNHP ALIYDKCVEE EDGFVGALDL FPPGYSSKAL EPQLSGKMLV LDYILAVTRS RSSDKVVLVS NYTQTLDLFE KLCRARRYLY VRLDGTMSIK KRAKVVERFN SPSSPDFVFM LSSKAGGCGL NLIGANRLVM FDPDWNPAND EQAMARVWRD GQKKTCYIYR LLSAGTIEEK IFQRQSHKKA LSSCVVDEEQ DVERHFSLGE LKELFILDEA SLSDTHDRLH CRRCVNSRQI RPPPDGSDCT SDLAGWNHCT DKWGLRDEVL QAAWDAASTA ITFVFHQRSH EEQRGLR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
84,352 Da
Sequence Positions
1-747aa; Full Length
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
603615
3D Structure
ModBase 3D Structure for Q92698
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RAD54L recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RAD54L. It may not necessarily be applicable to this product.

NCBI GI #
216548193
NCBI GeneID
8438
NCBI Accession #
NP_001136020.1
UniProt Primary Accession #
Q92698
UniProt Secondary Accession #
Q5TE31; Q6IUY3
UniProt Related Accession #
Q92698
GenBank Nucleotide #
NM_001142548.1
NCBI Official Full Name
DNA repair and recombination protein RAD54-like
NCBI Official Synonym Full Names
RAD54 like
NCBI Official Symbol
RAD54L
NCBI Official Synonym Symbols
HR54; hHR54; RAD54A; hRAD54
UniProt Protein Name
DNA repair and recombination protein RAD54-like
UniProt Synonym Protein Names
RAD54 homolog; hHR54; hRAD54
UniProt Gene Name
RAD54L
UniProt Synonym Gene Names
RAD54A; hHR54; hRAD54
NCBI Protein Information
DNA repair and recombination protein RAD54-like

NCBI Summary for RAD54L

The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]
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UniProt Comments for RAD54L

Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells.
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Research Articles on RAD54L

1. Nap1 binds to RAD54.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RAD54L recombinant protein

 Reference Product  PubMed Publications
 RAD51 recombinant protein  >44 publications with RAD54L and RAD51

Pathways associated with RAD54L recombinant protein

 Products by Pathway  Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram

Diseases associated with RAD54L recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >20 publications with RAD54L and Neoplasms
 Carcinoma Antibodies  >7 publications with RAD54L and Carcinoma
 Drug Toxicity Antibodies  >5 publications with RAD54L and Drug Toxicity
 Breast Neoplasms Antibodies  >5 publications with RAD54L and Breast Neoplasms
 Nervous System Diseases Antibodies  >4 publications with RAD54L and Nervous System Diseases
 Pancreatic Neoplasms Antibodies  >3 publications with RAD54L and Pancreatic Neoplasms
 Lymphoma Antibodies  >3 publications with RAD54L and Lymphoma
 Colorectal Neoplasms Antibodies  >3 publications with RAD54L and Colorectal Neoplasms
 Glioma Antibodies  >3 publications with RAD54L and Glioma
 Neoplasm Metastasis Antibodies  >2 publications with RAD54L and Neoplasm Metastasis

Organs/Tissues associated with RAD54L recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with RAD54L and Blood
 Brain Antibodies  >4 publications with RAD54L and Brain
 Bone Antibodies  >2 publications with RAD54L and Bone
 Spleen Antibodies  >2 publications with RAD54L and Spleen
 Lymph Node Antibodies  >2 publications with RAD54L and Lymph Node
 Embryonic Tissue Antibodies  >2 publications with RAD54L and Embryonic Tissue
 Testis Antibodies  >2 publications with RAD54L and Testis
 Lung Antibodies  >1 publications with RAD54L and Lung
 Lymph Antibodies  >1 publications with RAD54L and Lymph
 Liver Antibodies  >1 publications with RAD54L and Liver
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