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Matrix M2-1 (M2-1) Human Metapneumovirus Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1330200

MBS1330200 is a recombinant protein targeting M2-1. Also known as Recombinant Human metapneumovirus Matrix M2-1 (M2-1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$825 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Matrix M2-1 (M2-1), Recombinant Protein
Full Product Name
Recombinant Human metapneumovirus Matrix M2-1 (M2-1)
Product Gene Name
M2-1 recombinant protein
Product Synonym Gene Name
M2-1
Sequence
MSRKAPCKYE VRGKCNRGSE CKFNHNYWSW PDRYLLIRSN YLLNQLLRNT DRADGLSIIS GAGREDRTQD FVLGSTNVVQ GYIDDNQSIT KAAACYSLHN IIKQLQEVEV RQARDSKLSD SKHVALHNLI LSYMEMSKTP ASLINNLKRL PREKLKKLAK LIIDLSAGAD NDSSYALQDS ESINQVQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
21,234 Da
Sequence Positions
1-187, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q6WB97
Species
Human metapneumovirus (strain CAN97-83) (HMPV)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of M2-1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for M2-1. It may not necessarily be applicable to this product.

NCBI GI #
46852137
NCBI GeneID
2799940
NCBI Accession #
YP_012609.1
UniProt Primary Accession #
Q6WB97
GenBank Nucleotide #
NC_004148.2
NCBI Official Full Name
matrix protein M2-1
NCBI Official Symbol
M2
UniProt Protein Name
Matrix M2-1
UniProt Synonym Protein Names
Envelope-associated 22 kDa protein
Protein Family
Matrix M2
UniProt Gene Name
M2-1
NCBI Protein Information
M2-1

UniProt Comments for M2-1

Acts as a transcriptional elongation factor to prevent premature termination during transcription thus allowing complete synthesis of viral mRNAs. Functions also as a processivity and antitermination factor to permit transit of the polymerase through intergenic regions to access promoter distal genes. Plays a role in the association of the matrix protein with the nucleocapsid, which initiates assembly and budding ().
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Research Articles on M2-1

1. study identified the M2-2 protein of HMPV as a negative regulator of IFN-alpha production by plasmacytoid dendritic cells and uncovered the underlying mechanism

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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