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Probable ATP-Dependent RNA Helicase DDX5 (DDX5) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1330778

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and… More details

$1425 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Probable ATP-dependent RNA helicase DDX5 (Ddx5), Recombinant Protein
Full Product Name
Recombinant Mouse Probable ATP-dependent RNA helicase DDX5 (Ddx5)
Product Gene Name
Ddx5 recombinant protein
Product Synonym Gene Name
Ddx5
Sequence
MSSYSSDRDR GRDRGFGAPR FGGSRTGPLS GKKFGNPGEK LVKKKWNLDE LPKFEKNFYQ EHPDLARRTA QEVDTYRRSK EITVRGHNCP KPVLNFYEAN FPANVMDVIA RQNFTEPTAI QAQGWPVALS GLDMVGVAQT GSGKTLSYLL PAIVHINHQP FLERGDGPIC LVLAPTRELA QQVQQVAAEY CRACRLKSTC IYGGAPKGPQ IRDLERGVEI CIATPGRLID FLECGKTNLR RTTYLVLDEA DRMLDMGFEP QIRKIVDQIR PDRQTLMWSA TWPKEVRQLA EDFLKDYIHI NIGALELSAN HNILQIVDVC HDVEKDEKLI RLMEEIMSEK ENKTIVFVET KRRCDELTRK MRRDGWPAMG IHGDKSQQER DWVLNEFKHG KAPILIATDV ASRGLDVEDV KFVINYDYPN SSEDYIHRIG RTARSTKTGT AYTFFTPNNI KQVSDLISVL REANQAINPK LLQLVEDRGS GRSRGRGGMK DDRRDRYSAG KRGGFNTFRD RENYDRGYSN LLKRDFGAKT QNGVYSAANY TNGSFGSNFV SAGIQTSFRT GNPTGTYQNG YDSTQQYGSN VANMHNGMNQ QAYAYPLPQA APMIGYPMPT GYSQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
69,290 Da
Sequence Positions
1-614, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q61656
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ddx5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ddx5 purchase

MBS1330778 is a recombinant protein targeting Ddx5. Also known as Recombinant Mouse Probable ATP-dependent RNA helicase DDX5 (Ddx5). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Ddx5. It may not necessarily be applicable to this product.

NCBI GI #
341940436
NCBI GeneID
13207
NCBI Accession #
Q61656.2
UniProt Primary Accession #
Q61656
UniProt Secondary Accession #
E9Q105
UniProt Related Accession #
Q61656
NCBI Official Full Name
Probable ATP-dependent RNA helicase DDX5
NCBI Official Synonym Full Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
NCBI Official Symbol
Ddx5
NCBI Official Synonym Symbols
p68; Hlr1; G17P1; HUMP68; 2600009A06Rik
UniProt Protein Name
Probable ATP-dependent RNA helicase DDX5
UniProt Synonym Protein Names
DEAD box RNA helicase DEAD1; mDEAD1; DEAD box protein 5; RNA helicase p68
Protein Family
Probable ATP-dependent RNA helicase
UniProt Gene Name
Ddx5
UniProt Synonym Gene Names
Tnz2; mDEAD1
NCBI Protein Information
probable ATP-dependent RNA helicase DDX5

UniProt Comments for Ddx5

Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specific manner; the function probably involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.
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Research Articles on Ddx5

1. The results highlight a novel molecular mechanism underlying stability of neurogenesis-associated mRNAs controlled by the Klf4/Ddx5/Stau1 axis during mammalian corticogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ddx5 recombinant protein

 Reference Product  PubMed Publications
 Smad3 recombinant protein  >3 publications with Ddx5 and Smad3
 Tnf recombinant protein  >1 publications with Ddx5 and Tnf
 Smad4 recombinant protein  >1 publications with Ddx5 and Smad4

Pathways associated with Ddx5 recombinant protein

 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram

Organs/Tissues associated with Ddx5 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with Ddx5 and Blood
 Bone Antibodies  >7 publications with Ddx5 and Bone
 Kidney Antibodies  >6 publications with Ddx5 and Kidney
 Muscle Antibodies  >6 publications with Ddx5 and Muscle
 Prostate Antibodies  >6 publications with Ddx5 and Prostate
 Liver Antibodies  >6 publications with Ddx5 and Liver
 Connective Tissue Antibodies  >4 publications with Ddx5 and Connective Tissue
 Embryonic Tissue Antibodies  >4 publications with Ddx5 and Embryonic Tissue
 Testis Antibodies  >3 publications with Ddx5 and Testis
 Brain Antibodies  >3 publications with Ddx5 and Brain
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