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NADP-Dependent Malic Enzyme, Mitochondrial (ME3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1331510

MBS1331510 is a recombinant protein targeting ME3. Also known as Recombinant Human NADP-dependent malic enzyme, mitochondrial (ME3) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$455 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NADP-dependent malic enzyme, mitochondrial (ME3), Recombinant Protein
Full Product Name
Recombinant Human NADP-dependent malic enzyme, mitochondrial (ME3) , partial
Product Gene Name
ME3 recombinant protein
Product Synonym Gene Name
ME3
Sequence
RWTPTAPAQG CHSKPGPARP VPLKKRGYDV TRNPHLNKGM AFTLEERLQL GIHGLIPPCF LSQDVQLLRI MRYYERQQSD LDKYIILMTL QDRNEKLFYR VLTSDVEKFM PIVYTPTVGL ACQHYGLTFR RPRGLFITIH DKGHLATMLN SWPEDNIKAV VVTDGERILG LGDLGCYGMG IPVGKLALYT ACGGVNPQQC LPVLLDVGTN NEELLRDPLY IGLKHQRVHG KAYDDLLDEF MQAVTDKFGI NCLIQFEDFA NANAFRLLNK YRNKYCMFND DIQGTASVAV AGILAALRIT KNKLSNHVFV FQGAGEAAMG IAHLLVMALE KEGVPKAEAT RKIWMVDSKG LIVKGRSHLN HEKEMFAQDH PEVNSLEEVV RLVKPTAIIG VAAIAGAFTE QILRDMASFH ERPIIFALSN PTSKAECTAE KCYRVTEGRG IFASGSPFKS VTLEDGKTFI PGQGNNAYVF PGVALGVIAG GIRHIPDEIF LLTAEQIAQE VSEQHLSQGR LYPPLSTIRD VSLRIAIKVL DYAYKHNLAS YYPEPKDKEA FVRSLVYTPD YDSFTLD
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
67.2 kDa
Sequence Positions
24-590aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
604626
3D Structure
ModBase 3D Structure for Q16798
Species
Homo sapiens (Human)
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-Page of ME3 recombinant protein

Human ME3 Recombinant Protein – Cat# MBS1331510

Product References and Citations for ME3 recombinant protein

"Purification, cDNA cloning and heterologous expression of the human mitochondrial NADP(+)-dependent malic enzyme." Loeber G., Maurer-Fogy I., Schwendenwein R. Biochem. J. 304:687-692(1994)

Other Notes

Small volumes of ME3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ME3. It may not necessarily be applicable to this product.

NCBI GI #
62420882
NCBI GeneID
10873
NCBI Accession #
NP_001014811.1
UniProt Primary Accession #
Q16798
UniProt Secondary Accession #
Q8TBJ0; B7Z6V0
UniProt Related Accession #
Q16798
GenBank Nucleotide #
NM_001014811.1
NCBI Official Full Name
NADP-dependent malic enzyme, mitochondrial
NCBI Official Synonym Full Names
malic enzyme 3
NCBI Official Symbol
ME3
NCBI Official Synonym Symbols
NADP-ME
UniProt Protein Name
NADP-dependent malic enzyme, mitochondrial
UniProt Synonym Protein Names
Malic enzyme 3
UniProt Gene Name
ME3
UniProt Synonym Gene Names
NADP-ME
NCBI Protein Information
NADP-dependent malic enzyme, mitochondrial

NCBI Summary for ME3

Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
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Research Articles on ME3

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ME3 recombinant protein

 Products by Pathway  Pathway Diagram
 Pyruvate Metabolism Pathway antibodies  Pyruvate Metabolism Pathway Diagram
 Pyruvate Metabolism Pathway antibodies  Pyruvate Metabolism Pathway Diagram

Diseases associated with ME3 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13 publications with ME3 and Neoplasms
 Neoplasms, Experimental Antibodies  >4 publications with ME3 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >3 publications with ME3 and Kidney Diseases
 Respiratory Tract Diseases Antibodies  >3 publications with ME3 and Respiratory Tract Diseases
 Carcinoma Antibodies  >3 publications with ME3 and Carcinoma
 Prostatic Diseases Antibodies  >2 publications with ME3 and Prostatic Diseases
 Adenocarcinoma Antibodies  >2 publications with ME3 and Adenocarcinoma
 Liver Diseases Antibodies  >2 publications with ME3 and Liver Diseases
 Prostatic Neoplasms Antibodies  >2 publications with ME3 and Prostatic Neoplasms
 Drug Toxicity Antibodies  >2 publications with ME3 and Drug Toxicity

Organs/Tissues associated with ME3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with ME3 and Liver
 Kidney Antibodies  >4 publications with ME3 and Kidney
 Heart Antibodies  >3 publications with ME3 and Heart
 Lung Antibodies  >3 publications with ME3 and Lung
 Thymus Antibodies  >2 publications with ME3 and Thymus
 Testis Antibodies  >2 publications with ME3 and Testis
 Pancreas Antibodies  >2 publications with ME3 and Pancreas
 Prostate Antibodies  >2 publications with ME3 and Prostate
 Nerve Antibodies  >1 publications with ME3 and Nerve
 Skin Antibodies  >1 publications with ME3 and Skin
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