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Meckel Syndrome Type 1 Protein Homolog (MKS1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1335483

This protein localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding… More details

$1355 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Meckel syndrome type 1 protein homolog (Mks1), Recombinant Protein
Full Product Name
Recombinant Rat Meckel syndrome type 1 protein homolog (Mks1)
Product Gene Name
Mks1 recombinant protein
Product Synonym Gene Name
Mks1
Sequence
MAEAVWSTDT GEAVYRSRDP VRNLRLRVHL QRITSSNFLH YQPAAQMGKD LIDLATFKPP QAASGHRPDE EEEEEVIIGW QEKLFSQFEV DLYQNESACQ SPLDHQYRQE VLKLENSGGR KNRRIFTYTD SDRYTDLEEY CQKITTSAGE APSFLVERMA NVRRRRQDRR GVEGSKLKSR IITWEPSEDF IRNSHAINTP LQTMYIMADL GPYGKLGYKI HEHVLCVLKV DSNGVITVKP DFTGIKGPYR IETEGEKQEH TSAWKYTIDN VSSLAQPEEE EREQRVFKDL YGRHKEYLSS LVGTDFEMIA PGALRLFVNG EVVSARGYEH DNLYVHFFVE LPATNWSSPS FQQLSGVTQT CVTRSLGMDK VAYFSFPFTF EAFFLHEDES DESLPEWPVL YCKVLSLDFW QRYRVEGYGA VVLPVTPGSH TLTASTWRPM ELGLVAELRR FFIGGSLELE DPSYVRIPGT FKGERLSRFG FRTETTGTVT FRLHCLQQSR AFMESNSLRK QMRSVLDRLE GFSQQSSTHN VLEAFRRARR RMQEARESLP QDLVSPTGTL A
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
64,523 Da
Sequence Positions
1-561, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q499Q5
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mks1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mks1 purchase

MBS1335483 is a recombinant protein targeting Mks1. Also known as Recombinant Rat Meckel syndrome type 1 protein homolog (Mks1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Mks1. It may not necessarily be applicable to this product.

NCBI GI #
260064079
NCBI GeneID
287612
NCBI Accession #
NP_001030089.2
UniProt Primary Accession #
Q499Q5
UniProt Related Accession #
Q499Q5
GenBank Nucleotide #
NM_001034917.2
NCBI Official Full Name
Meckel syndrome type 1 protein homolog
NCBI Official Synonym Full Names
Meckel syndrome, type 1
NCBI Official Symbol
Mks1
UniProt Protein Name
Meckel syndrome type 1 protein homolog
Protein Family
Meckel syndrome type 1 protein
UniProt Gene Name
Mks1
NCBI Protein Information
Meckel syndrome type 1 protein homolog

UniProt Comments for Mks1

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes (). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.
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Research Articles on Mks1

1. MKS1 and MKS3 functions are required for ciliary structure and function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Mks1 recombinant protein

 Reference Product  PubMed Publications
 Tmem67 recombinant protein  >17 publications with Mks1 and Tmem67
 B9d1 recombinant protein  >6 publications with Mks1 and B9d1
 Ahi1 recombinant protein  >5 publications with Mks1 and Ahi1
 Tmem216 recombinant protein  >5 publications with Mks1 and Tmem216
 B9d2 recombinant protein  >4 publications with Mks1 and B9d2

Diseases associated with Mks1 recombinant protein

 Disease Name  Pubmed Publications
 Abnormalities, Multiple Antibodies  >22 publications with Mks1 and Abnormalities, Multiple
 Nervous System Diseases Antibodies  >20 publications with Mks1 and Nervous System Diseases
 Kidney Diseases Antibodies  >19 publications with Mks1 and Kidney Diseases
 Bardet-Biedl Syndrome Antibodies  >7 publications with Mks1 and Bardet-Biedl Syndrome
 Meckel syndrome type 1 Antibodies  >5 publications with Mks1 and Meckel syndrome type 1
 Disease Models, Animal Antibodies  >4 publications with Mks1 and Disease Models, Animal
 Fibrosis Antibodies  >3 publications with Mks1 and Fibrosis
 Hypertension Antibodies  >2 publications with Mks1 and Hypertension
 Weight Gain Antibodies  >1 publications with Mks1 and Weight Gain
 Hypospadias Antibodies  >1 publications with Mks1 and Hypospadias

Organs/Tissues associated with Mks1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >26 publications with Mks1 and Kidney
 Lung Antibodies  >1 publications with Mks1 and Lung
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