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Rb-Associated KRAB Zinc Finger Protein (RBAK) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1336479

This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein… More details

$1560 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RB-associated KRAB zinc finger protein (RBAK), Recombinant Protein
Full Product Name
Recombinant Human RB-associated KRAB zinc finger protein (RBAK)
Product Gene Name
RBAK recombinant protein
Product Synonym Gene Name
RBAK
Sequence
MNTLQGPVSF KDVAVDFTQE EWQQLDPDEK ITYRDVMLEN YSHLVSVGYD TTKPNVIIKL EQGEEPWIMG GEFPCQHSPE AWRVDDLIER IQENEDKHSR QAACINSKTL TEEKENTFSQ IYMETSLVPS SIIAHNCVSC GKNLESISQL ISSDGSYART KPDECNECGK TYHGEKMCEF NQNGDTYSHN EENILQKISI LEKPFEYNEC MEALDNEAVF IAHKRAYIGE KPYEWNDSGP DFIQMSNFNA YQRSQMEMKP FECSECGKSF CKKSKFIIHQ RAHTGEKPYE CNVCGKSFSQ KGTLTVHRRS HLEEKPYKCN ECGKTFCQKL HLTQHLRTHS GEKPYECSEC GKTFCQKTHL TLHQRNHSGE RPYPCNECGK SFSRKSALSD HQRTHTGEKL YKCNECGKSY YRKSTLITHQ RTHTGEKPYQ CSECGKFFSR VSYLTIHYRS HLEEKPYECN ECGKTFNLNS AFIRHRKVHT EEKSHECSEC GKFSQLYLTD HHTAHLEEKP YECNECGKTF LVNSAFDGHQ PLPKGEKSYE CNVCGKLFNE LSYYTEHYRS HSEEKPYGCS ECGKTFSHNS SLFRHQRVHT GEKPYECYEC GKFFSQKSYL TIHHRIHSGE KPYECSKCGK VFSRMSNLTV HYRSHSGEKP YECNECGKVF SQKSYLTVHY RTHSGEKPYE CNECGKKFHH RSAFNSHQRI HRRGNMNVLD VENL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
12,251 Da
Sequence Positions
1-714, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
608191
3D Structure
ModBase 3D Structure for Q9NYW8
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RBAK recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RBAK purchase

MBS1336479 is a recombinant protein targeting RBAK. Also known as Recombinant Human RB-associated KRAB zinc finger protein (RBAK). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for RBAK. It may not necessarily be applicable to this product.

NCBI GI #
325053658
NCBI GeneID
57786
NCBI Accession #
NP_001191385.1
UniProt Primary Accession #
Q9NYW8
UniProt Secondary Accession #
A6NDF2; A8KAK4; B2RN44; B9EGS1; F8W6M7
UniProt Related Accession #
Q9NYW8
GenBank Nucleotide #
NM_001204456.1
NCBI Official Full Name
RB-associated KRAB zinc finger protein
NCBI Official Synonym Full Names
RB associated KRAB zinc finger
NCBI Official Symbol
RBAK
NCBI Official Synonym Symbols
ZNF769
UniProt Protein Name
RB-associated KRAB zinc finger protein
UniProt Synonym Protein Names
RB-associated KRAB repressor; hRBaK; Zinc finger protein 769
Protein Family
RB-associated KRAB zinc finger protein
UniProt Gene Name
RBAK
UniProt Synonym Gene Names
ZNF769; hRBaK
NCBI Protein Information
RB-associated KRAB zinc finger protein

NCBI Summary for RBAK

This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]
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UniProt Comments for RBAK

May repress E2F-dependent transcription. May promote AR-dependent transcription.

Research Articles on RBAK

1. Studies indicate that data on the regulatory functions of the KRAB-ZFP in embryonic development and tumorgenesis will benefit the understanding of biological roles of KRAB-ZFP in different physiological and pathological states.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RBAK recombinant protein

 Reference Product  PubMed Publications
 RB1 recombinant protein  >1 publications with RBAK and RB1

Organs/Tissues associated with RBAK recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with RBAK and Blood
 Embryonic Tissue Antibodies  >1 publications with RBAK and Embryonic Tissue
 Brain Antibodies  >1 publications with RBAK and Brain
 Heart Antibodies  >1 publications with RBAK and Heart
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