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Ankyrin Repeat and Protein Kinase Domain-Containing Protein 1 (ANKK1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1339060

This protein belongs to the SerThr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism… More details

$1630 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ankyrin repeat and protein kinase domain-containing protein 1 (ANKK1), Recombinant Protein
Full Product Name
Recombinant Human Ankyrin repeat and protein kinase domain-containing protein 1 (ANKK1)
Product Gene Name
ANKK1 recombinant protein
Product Synonym Gene Name
ANKK1
Sequence
MAADPTELRL GSLPVFTRDD FEGDWRLVAS GGFSQVFQAR HRRWRTEYAI KCAPCLPPDA ASSDVNYLIE EAAKMKKIKF QHIVSIYGVC KQPLGIVMEF MANGSLEKVL STHSLCWKLR FRIIHETSLA MNFLHSIKPP LLHLDLKPGN ILLDSNMHVK ISDFGLSKWM EQSTRMQYIE RSALRGMLSY IPPEMFLESN KAPGPKYDVY SFAIVIWELL TQKKPYSGFN MMMIIIRVAA GMRPSLQPVS DQWPSEAQQM VDLMKRCWDQ DPKKRPCFLD ITIETDILLS LLQSRVAVPE SKALARKVSC KLSLRQPGEV NEDISQELMD SDSGNYLKRA LQLSDRKNLV PRDEELCIYE NKVTPLHFLV AQGSVEQVRL LLAHEVDVDC QTASGYTPLL IAAQDQQPDL CALLLAHGAD ANRVDEDGWA PLHFAAQNGD DGTARLLLDH GACVDAQERE GWTPLHLAAQ NNFENVARLL VSRQADPNLH EAEGKTPLHV AAYFGHVSLV KLLTSQGAEL DAQQRNLRTP LHLAVERGKV RAIQHLLKSG AVPDALDQSG YGPLHTAAAR GKYLICKMLL RYGASLELPT HQGWTPLHLA AYKGHLEIIH LLAESHANMG ALGAVNWTPL HLAARHGEEA VVSALLQCGA DPNAAEQSGW TPLHLAVQRS TFLSVINLLE HHANVHARNK VGWTPAHLAA LKGNTAILKV LVEAGAQLDV QDGVSCTPLQ LALRSRKQGI MSFLEGKEPS VATLGGSKPG AEMEI
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
84,632 Da
Sequence Positions
1-765, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
608774
3D Structure
ModBase 3D Structure for Q8NFD2
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ANKK1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ANKK1 purchase

MBS1339060 is a recombinant protein targeting ANKK1. Also known as Recombinant Human Ankyrin repeat and protein kinase domain-containing protein 1 (ANKK1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for ANKK1. It may not necessarily be applicable to this product.

NCBI GI #
30425444
NCBI GeneID
255239
NCBI Accession #
NP_848605.1
UniProt Primary Accession #
Q8NFD2
UniProt Related Accession #
Q8NFD2
GenBank Nucleotide #
NM_178510.1
NCBI Official Full Name
ankyrin repeat and protein kinase domain-containing protein 1
NCBI Official Synonym Full Names
ankyrin repeat and kinase domain containing 1
NCBI Official Symbol
ANKK1
NCBI Official Synonym Symbols
DRD2; PKK2
UniProt Protein Name
Ankyrin repeat and protein kinase domain-containing protein 1
UniProt Synonym Protein Names
Protein kinase PKK2; Sugen kinase 288; SgK288; X-kinase
Protein Family
Ankyrin repeat and protein kinase domain-containing protein
UniProt Gene Name
ANKK1
UniProt Synonym Gene Names
PKK2; SGK288; SgK288
NCBI Protein Information
ankyrin repeat and protein kinase domain-containing protein 1

NCBI Summary for ANKK1

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]
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Research Articles on ANKK1

1. The study provides an indication for the association of ANKK1 polymorphism in the form of higher substance consumption among alcohol dependent smokers, who are A1 carriers and thus may require higher attention of the treatment provider.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ANKK1 recombinant protein

 Reference Product  PubMed Publications
 DRD2 recombinant protein  >118 publications with ANKK1 and DRD2
 TTC12 recombinant protein  >12 publications with ANKK1 and TTC12
 CHRM2 recombinant protein  >3 publications with ANKK1 and CHRM2

Diseases associated with ANKK1 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4 publications with ANKK1 and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with ANKK1 and Brain Diseases
 Learning Disorders Antibodies  >2 publications with ANKK1 and Learning Disorders
 Neoplasms Antibodies  >2 publications with ANKK1 and Neoplasms
 Memory Disorders Antibodies  >1 publications with ANKK1 and Memory Disorders
 Seizures Antibodies  >1 publications with ANKK1 and Seizures
 Parkinson Disease Antibodies  >1 publications with ANKK1 and Parkinson Disease
 Delirium Antibodies  >1 publications with ANKK1 and Delirium
 Neurodegenerative Diseases Antibodies  >1 publications with ANKK1 and Neurodegenerative Diseases
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