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Developmental Pluripotency-Associated Protein 3 (DPPA3) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1339510

This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans,… More details

$800 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Developmental pluripotency-associated protein 3 (Dppa3), Recombinant Protein
Full Product Name
Recombinant Mouse Developmental pluripotency-associated protein 3 (Dppa3)
Product Gene Name
Dppa3 recombinant protein
Product Synonym Gene Name
Dppa3
Sequence
MEEPSEKVDP MKDPETPQKK DEEDALDDTD VLQPETLVKV MKKLTLNPGV KRSARRRSLR NRIAAVPVEN KSEKIRREVQ SAFPKRRVRT LLSVLKDPIA KMRRLVRIEQ RQKRLEGNEF ERDSEPFRCL CTFCHYQRWD PSENAKIGKN
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
17,670 Da
Sequence Positions
1-150, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8QZY3
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Dppa3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dppa3 purchase

MBS1339510 is a recombinant protein targeting Dppa3. Also known as Recombinant Mouse Developmental pluripotency-associated protein 3 (Dppa3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Dppa3. It may not necessarily be applicable to this product.

NCBI GI #
21218416
NCBI GeneID
73708
NCBI Accession #
NP_631964.1
UniProt Primary Accession #
Q8QZY3
UniProt Secondary Accession #
F6S6F5
UniProt Related Accession #
Q8QZY3
GenBank Nucleotide #
NM_139218.1
NCBI Official Full Name
developmental pluripotency-associated protein 3
NCBI Official Synonym Full Names
developmental pluripotency-associated 3
NCBI Official Symbol
Dppa3
NCBI Official Synonym Symbols
PCG7; PGC7; Stella; 2410075G02Rik
UniProt Protein Name
Developmental pluripotency-associated protein 3
UniProt Synonym Protein Names
Compaction-associated protein 1; Primordial germ cell protein 7
Protein Family
Developmental pluripotency-associated protein
UniProt Gene Name
Dppa3
UniProt Synonym Gene Names
Cap1p; Crg1; Pgc7
NCBI Protein Information
developmental pluripotency-associated protein 3

UniProt Comments for Dppa3

Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis.
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Research Articles on Dppa3

1. PRDM1 and STELLA, while overlapping in putative primordial germ cells, also co-localize in several other tissues

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Dppa3 recombinant protein

 Reference Product  PubMed Publications
 Nanog recombinant protein  >26 publications with Dppa3 and Nanog
 Pou5f1 recombinant protein  >24 publications with Dppa3 and Pou5f1
 Dazl recombinant protein  >12 publications with Dppa3 and Dazl
 Ddx4 recombinant protein  >5 publications with Dppa3 and Ddx4
 Zfp42 recombinant protein  >4 publications with Dppa3 and Zfp42
 Prdm14 recombinant protein  >3 publications with Dppa3 and Prdm14
 Dppa2 recombinant protein  >2 publications with Dppa3 and Dppa2

Diseases associated with Dppa3 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms, Germ Cell and Embryonal Antibodies  >5 publications with Dppa3 and Neoplasms, Germ Cell and Embryonal
 Breast Neoplasms Antibodies  >1 publications with Dppa3 and Breast Neoplasms
 Drug Toxicity Antibodies  >1 publications with Dppa3 and Drug Toxicity
 Pain Antibodies  >1 publications with Dppa3 and Pain

Organs/Tissues associated with Dppa3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >9 publications with Dppa3 and Embryonic Tissue
 Fertilized Ovum Antibodies  >4 publications with Dppa3 and Fertilized Ovum
 Mixed Antibodies  >1 publications with Dppa3 and Mixed
 Ovary Antibodies  >1 publications with Dppa3 and Ovary
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