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R-Spondin-2 (rspo2) Xenopus Laevis Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1340314

MBS1340314 is a recombinant protein targeting rspo2. Also known as Recombinant Xenopus laevis R-spondin-2 (rspo2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$880 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
R-spondin-2 (rspo2), Recombinant Protein
Full Product Name
Recombinant Xenopus laevis R-spondin-2 (rspo2)
Product Gene Name
Product Synonym Gene Name
rspo2
Sequence
QASRWRRSKR ASYGTNPICK GCLSCSKDNG CLRCQPKLFF FLRREGMRQY GECLQSCPPG YYGVRGPDMN RCSRCRIENC DSCFSRDFCI KCKSGFYSLK GQCFEECPEG FAPLDDTMVC VDGCEVGPWS EWGTCSRNNR TCGFKWGLET RTRQIVKKPA KDTIPCPTIA ESRRCKMAIR HCPGGKRTTK KKDKRNKKKK KKLLERAQEQ HSVVLATDRS SQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
27,879 Da
Sequence Positions
22-243, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q5UE90
Species
Xenopus laevis (African clawed frog)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of rspo2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for rspo2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
R-spondin-2
NCBI Official Synonym Full Names
R-spondin 2 L homeolog
NCBI Official Symbol
rspo2.L
NCBI Official Synonym Symbols
rspo2; CRISTIN2
UniProt Protein Name
R-spondin-2
UniProt Synonym Protein Names
Roof plate-specific spondin-2; XRspo2
Protein Family
UniProt Gene Name
rspo2
NCBI Protein Information
R-spondin-2

UniProt Comments for rspo2

Activator of the canonical Wnt signaling pathway by acting as a ligand for lgr4-6 receptors. Upon binding to lgr4-6 (lgr4, lgr5 or lgr6), lgr4-6 associate with phosphorylated lrp6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway (). Activates neural markers and promotes muscle formation. Overexpression blocks activin, nodal and BMP4 signaling, suggesting that it may negatively regulate the TGF-beta pathway.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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