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TBC1 Domain Family Member 15 (TBC1D15) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1340492

This gene encodes a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2Bub2Cdc16 domain. The encoded protein interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular… More details

$1530 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TBC1 domain family member 15 (TBC1D15), Recombinant Protein
Full Product Name
Recombinant Human TBC1 domain family member 15 (TBC1D15)
Product Gene Name
TBC1D15 recombinant protein
Product Synonym Gene Name
TBC1D15
Sequence
AAAGVVSGKI IYEQEGVYIH SSCGKTNDQD GLISGILRVL EKDAEVIVDW RPLDDALDSS SILYARKDSS SVVEWTQAPK ERGHRGSEHL NSYEAEWDMV NTVSFKRKPH TNGDAPSHRN GKSKWSFLFS LTDLKSIKQN KEGMGWSYLV FCLKDDVVLP ALHFHQGDSK LLIESLEKYV VLCESPQDKR TLLVNCQNKS LSQSFENLLD EPAYGLIQAG LLDRRKLLWA IHHWKKIKKD PYTATMIGFS KVTNYIFDSL RGSDPSTHQR PPSEMADFLS DAIPGLKINQ QEEPGFEVIT RIDLGERPVV QRREPVSLEE WTKNIDSEGR ILNVDNMKQM IFRGGLSHAL RKQAWKFLLG YFPWDSTKEE RTQLQKQKTD EYFRMKLQWK SISQEQEKRN SRLRDYRSLI EKDVNRTDRT NKFYEGQDNP GLILLHDILM TYCMYDFDLG YVQGMSDLLS PLLYVMENEV DAFWCFASYM DQMHQNFEEQ MQGMKTQLIQ LSTLLRLLDS GFCSYLESQD SGYLYFCFRW LLIRFKREFS FLDILRLWEV MWTELPCTNF HLLLCCAILE SEKQQIMEKH YGFNEILKHI NELSMKIDVE DILCKAEAIS LQMVKCKELP QAVCEILGLQ GSEVTTPDSD VGEDENVVMT PCPTSAFQSN ALPTLSASGA RNDSPTQIPV SSDVCRLTPA
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
78,572 Da
Sequence Positions
2-691, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
612662
3D Structure
ModBase 3D Structure for Q8TC07
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TBC1D15 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBC1D15 purchase

MBS1340492 is a recombinant protein targeting TBC1D15. Also known as Recombinant Human TBC1 domain family member 15 (TBC1D15). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for TBC1D15. It may not necessarily be applicable to this product.

NCBI GI #
299758464
NCBI GeneID
64786
NCBI Accession #
NP_001139685.2
UniProt Primary Accession #
Q8TC07
UniProt Secondary Accession #
Q9HA83; B4DMT9; B9A6L6; J3KNI9
UniProt Related Accession #
Q8TC07
GenBank Nucleotide #
NM_001146213.1
NCBI Official Full Name
TBC1 domain family member 15 isoform 3
NCBI Official Synonym Full Names
TBC1 domain family member 15
NCBI Official Symbol
TBC1D15
NCBI Official Synonym Symbols
RAB7-GAP
UniProt Protein Name
TBC1 domain family member 15
UniProt Synonym Protein Names
GTPase-activating protein RAB7; GAP for RAB7; Rab7-GAP
Protein Family
TBC1 domain family
UniProt Gene Name
TBC1D15
UniProt Synonym Gene Names
GAP for RAB7; Rab7-GAP
NCBI Protein Information
TBC1 domain family member 15

NCBI Summary for TBC1D15

This gene encodes a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. The encoded protein interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular trafficking. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
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UniProt Comments for TBC1D15

Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6 ().

Research Articles on TBC1D15

1. Demonstrate that TBC1D15 and TBC1D17 mediate proper autophagic encapsulation of mitochondria by regulating Rab7 activity at the interface between mitochondria and isolation membranes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TBC1D15 recombinant protein

 Reference Product  PubMed Publications
 CDC16 recombinant protein  >3 publications with TBC1D15 and CDC16

Diseases associated with TBC1D15 recombinant protein

 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >1 publications with TBC1D15 and Carcinoma, Hepatocellular
 Fatty Liver Antibodies  >1 publications with TBC1D15 and Fatty Liver

Organs/Tissues associated with TBC1D15 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with TBC1D15 and Liver
 Blood Antibodies  >1 publications with TBC1D15 and Blood
 Thymus Antibodies  >1 publications with TBC1D15 and Thymus
 Spleen Antibodies  >1 publications with TBC1D15 and Spleen
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