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Activin Receptor Type-2a (ACVR2A) Chicken Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1342792

This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric… More details

$1210 / 0.5 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Activin receptor type-2A (ACVR2A), Recombinant Protein
Full Product Name
Recombinant Chicken Activin receptor type-2A (ACVR2A), partial
Product Gene Name
ACVR2A recombinant protein
Product Synonym Gene Name
ACVR2A
Sequence
A ILGRSETQEC IYYNANWEKD KTNRSGIEPC YGDKDKRRHC FATWKNISGS IEIVKQGCWL DDINCYDRND CIEKKDSPEV FFCCCEGNMC NERFFYFPEM EVTQPTSNPV TPKPPLFNT
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
58,092 Da
Sequence Positions
20-139
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q90669
Species
Chicken
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ACVR2A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACVR2A purchase

MBS1342792 is a recombinant protein targeting ACVR2A. Also known as Recombinant Chicken Activin receptor type-2A (ACVR2A), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for ACVR2A. It may not necessarily be applicable to this product.

NCBI GI #
45382471
NCBI GeneID
396324
NCBI Accession #
NP_990698.1
UniProt Primary Accession #
Q90669
UniProt Secondary Accession #
Q90745
UniProt Related Accession #
Q90669
GenBank Nucleotide #
NM_205367.1
NCBI Official Full Name
activin receptor type-2A
NCBI Official Synonym Full Names
activin A receptor type 2A
NCBI Official Symbol
ACVR2A
UniProt Protein Name
Activin receptor type-2A
UniProt Synonym Protein Names
Activin receptor type IIA; ACTR-IIA; ACTRIIA
Protein Family
Activin receptor
UniProt Gene Name
ACVR2A
UniProt Synonym Gene Names
ACTR-IIA; ACTRIIA
NCBI Protein Information
activin receptor type-2A

UniProt Comments for ACVR2A

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. May modulate neuropeptide expression in dorsal root ganglia (DRG) neurons and ovarian follicle development.
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Research Articles on ACVR2A

1. Between broiler and layer lines, there were no significant changes in expression of the ACVR2A gene during embryonic stages but it varied significantly during the post-hatch period. The shRNA showed silencing of the ACVR2A gene under an in vitro cell culture system.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ACVR2A recombinant protein

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram

Diseases associated with ACVR2A recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with ACVR2A and Neoplasms
 Cardiovascular Diseases Antibodies  >2 publications with ACVR2A and Cardiovascular Diseases
 Craniofacial Abnormalities Antibodies  >2 publications with ACVR2A and Craniofacial Abnormalities
 Hypertension Antibodies  >1 publications with ACVR2A and Hypertension
 Heart Defects, Congenital Antibodies  >1 publications with ACVR2A and Heart Defects, Congenital
 Drug Toxicity Antibodies  >1 publications with ACVR2A and Drug Toxicity
 Diabetes Mellitus, Type 2 Antibodies  >1 publications with ACVR2A and Diabetes Mellitus, Type 2
 Disease Models, Animal Antibodies  >1 publications with ACVR2A and Disease Models, Animal
 Breast Neoplasms Antibodies  >1 publications with ACVR2A and Breast Neoplasms
 Nervous System Malformations Antibodies  >1 publications with ACVR2A and Nervous System Malformations

Organs/Tissues associated with ACVR2A recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >7 publications with ACVR2A and Other
 Embryonic Tissue Antibodies  >3 publications with ACVR2A and Embryonic Tissue
 Ovary Antibodies  >2 publications with ACVR2A and Ovary
 Muscle Antibodies  >1 publications with ACVR2A and Muscle
 Uncharacterized Tissue Antibodies  >1 publications with ACVR2A and Uncharacterized Tissue
 Brain Antibodies  >1 publications with ACVR2A and Brain
 Limb Antibodies  >1 publications with ACVR2A and Limb
 Head Antibodies  >1 publications with ACVR2A and Head
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