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Probable E3 Ubiquitin-Protein Ligase HECTD2 (HECTD2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1344825

MBS1344825 is a recombinant protein targeting Hectd2. Also known as Recombinant Mouse Probable E3 ubiquitin-protein ligase HECTD2 (Hectd2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1640 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Probable E3 ubiquitin-protein ligase HECTD2 (Hectd2), Recombinant Protein
Full Product Name
Recombinant Mouse Probable E3 ubiquitin-protein ligase HECTD2 (Hectd2)
Product Gene Name
Hectd2 recombinant protein
Product Synonym Gene Name
Hectd2
Sequence
MSEAARDLSP GAPPAVAAAA PEERKGKEPE REKLPPIVTA GAAAGLDRGS KGQISTFSSF VSTVTQKKEA AENRSSPTHL ALPNIRNVRD LPPICLDVRQ KQRMSVEALP SEVKVPPLPE PSLPSQPKTV KDFEEDLEKA EATGNWKTVH AFYITAFDSF TELNTAFKKD ATASFNTIED SGLNANLVNA VFDALLNTPQ DIQKSVLKGI INSLLQEWKG PRTKDDLRAY FILLQNPQFN ITSTYVIYAH LLRQIATLVE ADHHFLVHWL KKLSQKKFKQ LVERLLQFVS LRLFPAKPEE FPPLTKCTWW IPSAAKVLAL LNTANNLVHP PLVPYTDFYN STLDHIDLME EYHTWQSFGN SHRFSFCQYP FVISIAAKKI IIQRDSEQQM ISIARQSLVD KVSRRQRPDM NMLFLNMKVR RTHLVSDSLD ELTRKRADLK KKLKVTFVGE AGLDMGGLTK EWFLLLIRQI FHPDYGMFTY HKDSHCHWFS SFKCDNYSEF RLVGILMGLA VYNSITLDIR FPPCCYKKLL SPPVVPSDQS TPVGICSVTI DDLCQVMPEL AHGLKELLSY EGNVEEDFYS TFQVFQEEFG VIKSYNLKPG GDKIPVTNQN RREYVQLYTD FLLNKSIYKQ FAAFYCGFHS VCASNALMLL RPEEVEILVC GSPELDMHAL QRSTQYDGYA KTDLTIRYFW DVVLGFPLEL QKKLLHFTTG SDRVPVGGMA DLNFKISKNE TSTNWLPVAH TCFNQLCLPP YKSKKDLKQK LIIGISNSEG FGLE
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
87,773 Da
Sequence Positions
1-774, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8CDU6
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Hectd2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Hectd2. It may not necessarily be applicable to this product.

NCBI GI #
254939511
NCBI GeneID
226098
NCBI Accession #
NP_001156943.1
UniProt Primary Accession #
Q8CDU6
UniProt Secondary Accession #
Q8CBQ9; E9QK99
UniProt Related Accession #
Q8CDU6
GenBank Nucleotide #
NM_001163471.1
NCBI Official Full Name
probable E3 ubiquitin-protein ligase HECTD2 isoform 1
NCBI Official Synonym Full Names
HECT domain E3 ubiquitin protein ligase 2
NCBI Official Symbol
Hectd2
NCBI Official Synonym Symbols
AW212605; 4921524L07; A630025O09Rik
UniProt Protein Name
Probable E3 ubiquitin-protein ligase HECTD2
UniProt Synonym Protein Names
HECT domain-containing protein 2; HECT-type E3 ubiquitin transferase HECTD2
Protein Family
Probable E3 ubiquitin-protein ligase
UniProt Gene Name
Hectd2
NCBI Protein Information
probable E3 ubiquitin-protein ligase HECTD2

UniProt Comments for Hectd2

Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Research Articles on Hectd2

1. studies describe an unreported innate immune pathway and suggest that mutation or antagonism of the E3 ligase HECTD2 results in reduced severity of lung inflammation by selectively modulating the abundance of the anti-inflammatory protein PIAS1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Hectd2 recombinant protein

 Reference Product  PubMed Publications
 Rarb recombinant protein  >2 publications with Hectd2 and Rarb
 Cpne8 recombinant protein  >2 publications with Hectd2 and Cpne8
 Sprn recombinant protein  >2 publications with Hectd2 and Sprn

Diseases associated with Hectd2 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with Hectd2 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with Hectd2 and Brain Diseases

Organs/Tissues associated with Hectd2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with Hectd2 and Brain
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