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Melanoma Inhibitory Activity Protein 2 (MIA2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1345322

MBS1345322 is a recombinant protein targeting Mia2. Also known as Recombinant Mouse Melanoma inhibitory activity protein 2 (Mia2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1295 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Melanoma inhibitory activity protein 2 (Mia2), Recombinant Protein
Full Product Name
Recombinant Mouse Melanoma inhibitory activity protein 2 (Mia2)
Product Gene Name
Mia2 recombinant protein
Product Synonym Gene Name
Mia2
Sequence
TKLLAHLKKC GDLECETLIS RVLALRDYTG PDCRYLNFTT GEEISVYVKL GGDREDLWAG SKGKDFGFFP RDAVEIEEVF ISEEVEMPTK SDFLCLLGEG YIFGSEQSEL NSEDDEEHMY PYEKDEDQNY NIYEGDFQPE PDLYAAAEGT LLEDQIPASE APDDFRFSSE WKAWEGAGSQ GGGEQDYTAD SDQDLPSLSK PERQGWFGLG TEEAEEKVFE SDTEPTQELA LEEESDLEKL HSGEPQVELE QEPKSETLEF SSVPDEEYEL ESETESILKP QASGWFGEGL TSYLGFGNEE AGLELLSKES NPPLQDIPSS VPPDEEVPAP CREISTDKED AVINDSSVLS PSWFYYGFGM LGFTNADEDN IVSDKGENED GEVDNLKHPI GSDFDPEKEQ ERKIVTVETE DQAGTESVLE KTDESGSMQY LKKFFDNPWG FQSLPEDTEL PFSKKMLDQD DIVENDKIEE LSTENSPTGS MKDPVMLASR YVLSG
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
57,777 Da
Sequence Positions
23-517, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q91ZV0
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mia2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Mia2. It may not necessarily be applicable to this product.

NCBI GI #
28893435
NCBI GeneID
338320
NCBI Accession #
NP_796295.1
UniProt Primary Accession #
Q91ZV0
UniProt Related Accession #
Q8R311; Q91ZV0
GenBank Nucleotide #
NM_177321.2
NCBI Official Full Name
melanoma inhibitory activity protein 2 isoform 2
NCBI Official Synonym Full Names
melanoma inhibitory activity 2
NCBI Official Symbol
Mia2
NCBI Official Synonym Symbols
Mea6; Mgea; Mgea6; Ctage5; D12Bwg0579e
UniProt Protein Name
Melanoma inhibitory activity protein 2
Protein Family
Melanoma inhibitory activity protein
UniProt Gene Name
Mia2
NCBI Protein Information
melanoma inhibitory activity protein 2; cTAGE family member 5

NCBI Summary for Mia2

This gene encodes a protein that is involved in endoplasmic reticulum-to-Golgi trafficking and regulation of cholesterol metabolism. Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species. Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding diverse isoforms. A mutation in this gene (couch-potato or cpto) may result in low levels of plasma cholesterol and triglycerides. [provided by RefSeq, Sep 2016]
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UniProt Comments for Mia2

Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Isoform 1 plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (). Thereby, may play a role in cholesterol and triglyceride homeostasis (PubMed:21807889).
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Research Articles on Mia2

1. cTAGE5 deletion in pancreatic beta cells impairs proinsulin trafficking and insulin biogenesis in mice.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Mia2 recombinant protein

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >4 publications with Mia2 and Liver Diseases
 Neoplasms Antibodies  >3 publications with Mia2 and Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with Mia2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >3 publications with Mia2 and Liver Neoplasms
 Fibrosis Antibodies  >2 publications with Mia2 and Fibrosis
 Occupational Diseases Antibodies  >1 publications with Mia2 and Occupational Diseases
 Nervous System Diseases Antibodies  >1 publications with Mia2 and Nervous System Diseases
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