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Crumbs Homolog 2 (CRB2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1345547

MBS1345547 is a recombinant protein targeting Crb2. Also known as Recombinant Mouse Crumbs homolog 2 (Crb2) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$905 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Crumbs homolog 2 (Crb2), Recombinant Protein
Full Product Name
Recombinant Mouse Crumbs homolog 2 (Crb2) , partial
Product Gene Name
Product Synonym Gene Name
Crb2
Sequence
QNTTFSVVSG SSVWGLVPAA ASLGLALRFR TTLLAGTLAT LKDTRDSLEL VLVGAVLQAT LSRHGTAVLI LTLPDLALND GHWHQVEVTL HLGTLELRLW HEGCPGQLCV ASGPVATGPT ASVASGPPGS YSIYLGGGVF AGCFQDVRVE GHLLLPEELK GTVLLGCERR EPCQPLPCAH GGACVDLWTH FRCDCPRPYR GATCTDEVPA ATFGLGGATS SASFLLHQLG PNLTVSFFLR TREPAGLLLQ FANDSVASLT VFLSEGQIRA EGLGHPAVVL PGRWDDGLPH LVMLSFGPDQ LQDLGQRLYV GGRFYPDDTQ LWGGPFRGCL QDLQLNSIHL PFFSS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
134,760 Da
Sequence Positions
441-785aa, Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q80YA8
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Crb2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Crb2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein crumbs homolog 2
NCBI Official Synonym Full Names
crumbs family member 2
NCBI Official Symbol
Crb2
NCBI Official Synonym Symbols
BC043114; 5930402A21
UniProt Protein Name
Protein crumbs homolog 2
UniProt Synonym Protein Names
Crumbs-like protein 2
Protein Family
UniProt Gene Name
Crb2
UniProt Synonym Gene Names
crumbs2
NCBI Protein Information
protein crumbs homolog 2

UniProt Comments for Crb2

Apical polarity protein that plays a central role during the epithelial-to-mesenchymal transition (EMT) at gastrulation, when newly specified mesodermal cells move inside the embryo (PubMed:26496195, PubMed:27870829). Acts by promoting cell ingression, the process by which cells leave the epithelial epiblast and move inside the embryo to form a new tissue layer (PubMed:27870829). The anisotropic distribution of CRB2 and MYH10/myosin-IIB at cell edges define which cells will ingress: cells with high apical CRB2 are probably extruded from the epiblast by neighboring cells with high levels of apical MYH10/myosin-IIB (PubMed:27870829). Also required for maintenance of the apical polarity complex during development of the cortex.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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