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Arginase-2, Mitochondrial (ARG2) Rabbit Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1347446

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function.… More details

$1045 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Arginase-2, mitochondrial (ARG2), Recombinant Protein
Full Product Name
Recombinant Rabbit Arginase-2, mitochondrial (ARG2)
Product Gene Name
ARG2 recombinant protein
Product Synonym Gene Name
ARG2
Sequence
VHSVAVIGAP FSQGQKRKGV ECGPAAIRDA GLVKRLSDLG CRLKDYGDLS FTPVPKDDLY NNLIVNPRSV GLANQELAEV VNRAVSGGYS CVTVGGDHSL AIGTISGHAR HCPDLCVVWV DAHADINTPL TTSSGNLHGQ PVSFLLRELQ DKVPQLPGFS WIKPCISSPS IVYIGLRDVD PPEHFILKKY DIQYFSMRDI DRLGIQKVME QTFDLLIGKK QRPIHLSFDI DAFDPTLAPA TGTPGCGGAD LSRRMYISEE IHNTGLLSAL DLVEVNPRLA ASDEEAKATA SLAVDVIASS FGQTREGGHT VYEQLPPPSS PHESENAERV RI
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
38,393 Da
Sequence Positions
23-354, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q4VK78
Species
Rabbit
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ARG2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARG2 purchase

MBS1347446 is a recombinant protein targeting ARG2. Also known as Recombinant Rabbit Arginase-2, mitochondrial (ARG2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for ARG2. It may not necessarily be applicable to this product.

NCBI GI #
126723317
NCBI GeneID
100008967
NCBI Accession #
NP_001075650.1
UniProt Primary Accession #
Q4VK78
UniProt Related Accession #
Q4VK78
GenBank Nucleotide #
NM_001082181.1
NCBI Official Full Name
arginase-2, mitochondrial
NCBI Official Symbol
ARG2
UniProt Protein Name
Arginase-2, mitochondrial
UniProt Synonym Protein Names
Arginase II; Type II arginase
Protein Family
Arginase
UniProt Gene Name
ARG2
NCBI Protein Information
arginase-2, mitochondrial

UniProt Comments for ARG2

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signaling, which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction. Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling. Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity.
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Research Articles on ARG2

1. Kidneys from circulation-restricted fetuses showed arginase-2 protein induction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ARG2 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >25 publications with ARG2 and Neoplasms
 Nervous System Diseases Antibodies  >17 publications with ARG2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >16 publications with ARG2 and Disease Models, Animal
 Inflammation Antibodies  >12 publications with ARG2 and Inflammation
 Brain Diseases Antibodies  >12 publications with ARG2 and Brain Diseases
 Lung Diseases Antibodies  >11 publications with ARG2 and Lung Diseases
 Cardiovascular Diseases Antibodies  >10 publications with ARG2 and Cardiovascular Diseases
 Pain Antibodies  >10 publications with ARG2 and Pain
 Vascular Diseases Antibodies  >9 publications with ARG2 and Vascular Diseases
 Asthma Antibodies  >9 publications with ARG2 and Asthma

Organs/Tissues associated with ARG2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Whole Body Antibodies  >1 publications with ARG2 and Whole Body
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