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Zinc Finger Protein 385a (ZNF385A) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1352632

MBS1352632 is a recombinant protein targeting ZNF385A. Also known as Recombinant Human Zinc finger protein 385A (ZNF385A). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1120 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Zinc finger protein 385A (ZNF385A), Recombinant Protein
Full Product Name
Recombinant Human Zinc finger protein 385A (ZNF385A)
Product Gene Name
ZNF385A recombinant protein
Product Synonym Gene Name
ZNF385A
Sequence
MILGSLSRAG PLPLLRQPPI MQPPLDLKQI LPFPLEPAPT LGLFSNYSTM DPVQKAVLSH TFGGPLLKTK RPVISCNICQ IRFNSQSQAE AHYKGNRHAR RVKGIEAAKT RGREPGVREP GDPAPPGSTP TNGDGVAPRP VSMENGLGPA PGSPEKQPGS PSPPSIPETG QGVTKGEGGT PAPASLPGGS KEEEEKAKRL LYCALCKVAV NSLSQLEAHN KGTKHKTILE ARSGLGPIKA YPRLGPPTPG EPEAPAQDRT FHCEICNVKV NSEVQLKQHI SSRRHRDGVA GKPNPLLSRH KKSRGAGELA GTLTFSKELP KSLAGGLLPS PLAVAAVMAA AAGSPLSLRP APAAPLLQGP PITHPLLHPA PGPIRTAHGP ILFSPY
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
32,291 Da
Sequence Positions
1-386, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
609124
3D Structure
ModBase 3D Structure for Q96PM9
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ZNF385A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZNF385A. It may not necessarily be applicable to this product.

NCBI GI #
195972903
NCBI GeneID
25946
NCBI Accession #
NP_001124439.1
UniProt Primary Accession #
Q96PM9
UniProt Secondary Accession #
Q5VH53; Q9H7R6; Q9UFU3; B2RDN5; B4DKH2; F1T0F1; J3KNS3
UniProt Related Accession #
Q96PM9
GenBank Nucleotide #
NM_001130967.2
NCBI Official Full Name
zinc finger protein 385A isoform a
NCBI Official Synonym Full Names
zinc finger protein 385A
NCBI Official Symbol
ZNF385A
NCBI Official Synonym Symbols
HZF; RZF; ZFP385; ZNF385
UniProt Protein Name
Zinc finger protein 385A
UniProt Synonym Protein Names
Hematopoietic zinc finger protein; Retinal zinc finger protein
Protein Family
Zinc finger protein
UniProt Gene Name
ZNF385A
UniProt Synonym Gene Names
HZF; RZF; ZNF385
NCBI Protein Information
zinc finger protein 385A

NCBI Summary for ZNF385A

Zinc finger proteins, such as ZNF385A, are regulatory proteins that act as transcription factors, bind single- or double-stranded RNA, or interact with other proteins (Sharma et al., 2004 [PubMed 15527981]).[supplied by OMIM, Oct 2008]

UniProt Comments for ZNF385A

RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction. Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes. May also regulate the ubiquitination and stability of CDKN1A promoting DNA damage-induced cell cycle arrest. Also plays a role in megakaryocytes differentiation.
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Research Articles on ZNF385A

1. Brain gene expression of PADI2, ZNF385A, PSD2, and A2ML1 and DNA methylation dysregulations are implicated in the alteration of brain tissue properties associated with late-life cognitive decline above and beyond the influence of common neuropathologic conditions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ZNF385A recombinant protein

 Reference Product  PubMed Publications
 TP53 recombinant protein  >1 publications with ZNF385A and TP53

Pathways associated with ZNF385A recombinant protein

 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram

Organs/Tissues associated with ZNF385A recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with ZNF385A and Eye
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