Human VTI1B Recombinant Protein – Cat# MBS1355658

Vesicle Transport Through Interaction with T-Snares Homolog 1b (VTI1B) Human Recombinant Protein

Name: VTI1B Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1355658
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1355658

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be… More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B), Recombinant Protein

Full Product Name

Recombinant Human Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B), partial

Product Gene Name

VTI1B recombinant protein

Product Synonym Names

Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1

Sequence

SSEHFEKLHE IFRGLHEDLQ GVPERLLGTA GTEEKKKLIR DFDEKQQEAN ETLAEMEEEL RYAPLSFRNP MMSKLRNYRK DLAKLHREVR STPLTATPGG RGDMKYGIYA VENEHMNRLQ SQRAMLLQGT ESLNRATQSI ERSHRIATET DQIGSEIIEE LGEQRDQLER TKSRLVNTSE NLSKSRKILR SMSRKVTTNK LL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Molecular Weight

39.4 kDa

Sequence Positions

7-208aa; Partial

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

603207

3D Structure

ModBase 3D Structure for Q9UEU0

Product Categories/Family for VTI1B recombinant protein

Transport

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for VTI1B recombinant protein

A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways.Fischer von Mollard G., Stevens T.H.J. Biol. Chem. 273:2624-2630(1998)

Other Notes

Small volumes of VTI1B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VTI1B purchase

MBS1355658 is a recombinant protein targeting VTI1B. Also known as Recombinant Human Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for VTI1B. It may not necessarily be applicable to this product.

NCBI GI #

5454166

NCBI GeneID

10490

NCBI Accession #

NP_006361.1

UniProt Primary Accession #

Q9UEU0

UniProt Secondary Accession #

O43547; Q96J28

UniProt Related Accession #

Q9UEU0

GenBank Nucleotide #

NM_006370.2

NCBI Official Full Name

vesicle transport through interaction with t-SNAREs homolog 1B

NCBI Official Synonym Full Names

vesicle transport through interaction with t-SNAREs 1B

NCBI Official Symbol

VTI1B

NCBI Official Synonym Symbols

VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE

UniProt Protein Name

Vesicle transport through interaction with t-SNAREs homolog 1B

UniProt Synonym Protein Names

Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1

Protein Family

Vesicle transport through interaction with t-SNAREs

UniProt Gene Name

VTI1B

UniProt Synonym Gene Names

VTI1; VTI1L; VTI1L1; VTI2

UniProt Entry Name

VTI1B_HUMAN

NCBI Protein Information

vesicle transport through interaction with t-SNAREs homolog 1B

UniProt Comments for VTI1B

VTI1B: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. Belongs to the VTI1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: cell soma; cytoplasm; Golgi apparatus; integral to membrane; intracellular membrane-bound organelle; late endosome membrane; lysosomal membrane; perinuclear region of cytoplasm; recycling endosome; synaptic vesicle; vesicle

Molecular Function: chloride channel inhibitor activity; protein binding; SNAP receptor activity; SNARE binding

Biological Process: cell proliferation; intracellular protein transport; vesicle docking during exocytosis; vesicle-mediated transport

Research Articles on VTI1B

1. Vti1b-dependent tethering of Lytic granule and CD3-endo determines accumulation, docking, and efficient lytic granule secretion at the immunological synapse.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with VTI1B recombinant protein

Reference Product	PubMed Publications
VAMP7 recombinant protein	>5 publications with VTI1B and VAMP7
STX7 recombinant protein	>4 publications with VTI1B and STX7
STX8 recombinant protein	>4 publications with VTI1B and STX8
CLINT1 recombinant protein	>3 publications with VTI1B and CLINT1
STX6 recombinant protein	>3 publications with VTI1B and STX6
VAMP4 recombinant protein	>1 publications with VTI1B and VAMP4
STX4 recombinant protein	>1 publications with VTI1B and STX4

Pathways associated with VTI1B recombinant protein

Products by Pathway	Pathway Diagram
SNARE Interactions In Vesicular Transport Pathway antibodies	SNARE Interactions In Vesicular Transport Pathway Diagram
SNARE Interactions In Vesicular Transport Pathway antibodies	SNARE Interactions In Vesicular Transport Pathway Diagram

Diseases associated with VTI1B recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>2 publications with VTI1B and Disease Models, Animal
Necrosis Antibodies	>2 publications with VTI1B and Necrosis
Carcinoma Antibodies	>1 publications with VTI1B and Carcinoma
Breast Neoplasms Antibodies	>1 publications with VTI1B and Breast Neoplasms
Edema Antibodies	>1 publications with VTI1B and Edema
Inflammation Antibodies	>1 publications with VTI1B and Inflammation

Organs/Tissues associated with VTI1B recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with VTI1B and Blood
Nerve Antibodies	>3 publications with VTI1B and Nerve
Bone Antibodies	>2 publications with VTI1B and Bone
Liver Antibodies	>2 publications with VTI1B and Liver
Bone Marrow Antibodies	>2 publications with VTI1B and Bone Marrow
Lung Antibodies	>2 publications with VTI1B and Lung
Brain Antibodies	>2 publications with VTI1B and Brain
Ganglia Antibodies	>1 publications with VTI1B and Ganglia
Salivary Gland Antibodies	>1 publications with VTI1B and Salivary Gland
Mouth Antibodies	>1 publications with VTI1B and Mouth