Russells Viper Venom Factor X Activator (SVMP) Protease

Name: SVMP Protease; MyBioSource
Brand: MyBioSource
SKU: MBS135612
Price: 1045 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS135612

Purified from Russells Viper Venom. Zinc dependant endopeptidase that activates Factor X to Xa and Factor IX to IXa-alpha. This protease is inhibited by EDTA and o-phenanthroline. RVV-X is a glycoprotein that consists of two disulfide linked subunits of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Russells Viper Venom Factor X Activator (SVMP), Protease

Full Product Name

Russells Viper Venom Factor X Activator

Product Gene Name

SVMP protease

Host

Snake venom

Form/Format

Liquid

Purity/Purification

>95% by SDS-PAGE analysis

Concentration

4.4 mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C. Shelf Life: 12 months from delivery

Molecular Weight

70,000

3D Structure

ModBase 3D Structure for P86536

Volume

.227ml

Aliquot

1 x 1.0mg

Buffer

50% Glycerol

Extinction Coefficient

1.34

Product Categories/Family for SVMP protease

Snake Venom Proteases; Russells Viper Proteases

Other Notes

Small volumes of SVMP protease vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SVMP purchase

MBS135612 is a protease targeting SVMP. Also known as Russells Viper Venom Factor X Activator. Host: Snake venom.

Additional Details

NCBI/Uniprot data below describe general gene information for SVMP. It may not necessarily be applicable to this product.

NCBI GI #

298289237

NCBI Accession #

P86536.1

UniProt Primary Accession #

P86536

NCBI Official Full Name

Coagulation factor X-activating enzyme heavy chain

UniProt Protein Name

Coagulation factor X-activating enzyme heavy chain

UniProt Synonym Protein Names

Coagulation factor X-activating enzyme chain alpha; RVV-X heavy chain; Snake venom metalloproteinase

UniProt Gene Name

SVMP

UniProt Synonym Gene Names

SVMP

UniProt Entry Name

VM3CX_DABRR

UniProt Comments for SVMP

Function: Catalytic subunit of coagulation factor X-activating enzyme, a zinc-protease enzyme that acts in hemostasis. Activates coagulation factor X (F10) by cleaving the Arg-Ile bond at position 234 and is also able to activate coagulation factor IX (F9) and protein C (PROC) by specific cleavage of Arg-Ile and Arg-Val bonds

By similarity. UniProtKB Q7LZ61

Catalytic activity: Specifically activates several components of the blood clotting system, including coagulation factor X, coagulation factor IX and protein C by cleavage of Arg-|-Xaa bonds. Has no action on insulin B chain. UniProtKB Q7LZ61

Cofactor: Binds 1 zinc ion per subunit

By similarity. UniProtKB Q4VM07

Subunit structure: Heterotrimer; disulfide-linked. The heterotrimer consists of 1 heavy chain and 2 light chains: LC1 and LC2

By similarity. UniProtKB Q7LZ61

Subcellular location: Secreted Ref.1.

Tissue specificity: Expressed by the venom gland. Ref.1

Post-translational modification: N-glycosylated

By similarity. UniProtKB Q7LZ61

Sequence similarities: Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIId sub-subfamily.Contains 1 peptidase M12B domain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.