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Pancreatic Elastase (CELA1) Rat Protease

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS135614

Chromatographically prepared from the euglobin fraction of pancreas by the method of Lewis et al. (1) then twice crystallized. Supplied as salt free lyophilized powder. The protein is stable 9-12 months when stored at 5 C and does not contain trypsin or c More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
pancreatic elastase (CELA1), Protease
Full Product Name
Rat pancreatic elastase
Product Gene Name
Host
Rat pancreas
Form/Format
Lyophilized powder
Purity/Purification
>95% by SDS-PAGE analysis
Preparation and Storage
Store at 4 degree C. Shelf Life: 12 months from delivery
Molecular Weight
25,700
Chromosome Location
Chromosome: 7; NC_005106.3 (140110767..140123423, complement). Location: 7q36
3D Structure
ModBase 3D Structure for P00773
Specific Activity
2.0 U/mg (One unit will hydrolyze 1 umole of Suc-Ala-Ala-Ala-pNA per minute at pH 8.8 and 37C)
Buffer
Salt free
Extinction Coefficient
0.985

Other Notes

Small volumes of CELA1 protease vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CELA1 purchase

MBS135614 is a protease targeting CELA1. Also known as Rat pancreatic elastase. Host: Rat pancreas.

Additional Details

NCBI/Uniprot data below describe general gene information for CELA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chymotrypsin-like elastase family member 1
NCBI Official Synonym Full Names
chymotrypsin-like elastase family, member 1
NCBI Official Symbol
Cela1
NCBI Official Synonym Symbols
Ela1; ELAI1; RATELAI1
UniProt Protein Name
Chymotrypsin-like elastase family member 1
UniProt Synonym Protein Names
Elastase-1
UniProt Gene Name
Cela1
UniProt Synonym Gene Names
Ela1
UniProt Entry Name
CELA1_RAT
NCBI Protein Information
chymotrypsin-like elastase family member 1; elastase-1; elastase 1, pancreatic

NCBI Summary for CELA1

catalyzes the hydrolysis of elastin and other proteins [RGD, Feb 2006]

UniProt Comments for CELA1

Function: Acts upon elastin.

Catalytic activity: Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-Xaa.

Cofactor: Binds 1 calcium ion per subunit

By similarity.

Subcellular location: Secreted.

Tissue specificity: Pancreas.

Sequence similarities: Belongs to the peptidase S1 family. Elastase subfamily.Contains 1 peptidase S1 domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with CELA1 protease

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with CELA1 and Carcinoma
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