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Fibrinogen (FGA) Rat Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS135649

Prepared from fresh rat plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw protein in a 37C water bath. Aliquot and freeze the unused portion. Keep fibrinogen at 25-37C, aliquot and flash freeze unused More details

$835 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fibrinogen (FGA), Active Protein
Full Product Name
Rat Fibrinogen
Product Gene Name
FGA active protein
Host
Rat plasma
Form/Format
Frozen liquid
Purity/Purification
>95% by SDS-PAGE analysis
Concentration
10.0 mg/ml (lot specific)
Preparation and Storage
Store at -70 degree C. Shelf Life: 3 years from delivery
Molecular Weight
340,000
Chromosome Location
Chromosome: 2; NC_005101.3 (201412182..201428140). Location: 2q34
3D Structure
ModBase 3D Structure for P06399
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Specific Activity
>90% Clottable
Buffer
0.02M Sodium Citrate-HCl; pH 7.4
Extinction Coefficient
1.51

Product Categories/Family for FGA active protein

Fibrinogen; Rat Fibrinogen

Other Notes

Small volumes of FGA active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGA purchase

MBS135649 is an active protein targeting FGA. Also known as Rat Fibrinogen. Host: Rat plasma.

Additional Details

NCBI/Uniprot data below describe general gene information for FGA. It may not necessarily be applicable to this product.

NCBI GI #
1706800
NCBI GeneID
361969
NCBI Accession #
P06399.3
UniProt Primary Accession #
P06399
UniProt Secondary Accession #
P14480; P02680
UniProt Related Accession #
P06399
NCBI Official Full Name
Fibrinogen alpha chain
NCBI Official Synonym Full Names
fibrinogen alpha chain
NCBI Official Symbol
Fga
NCBI Official Synonym Symbols
Fba5e; Ac1873
UniProt Protein Name
Fibrinogen alpha chain
Protein Family
Fibrinogen
UniProt Gene Name
Fga
UniProt Entry Name
FIBA_RAT
NCBI Protein Information
fibrinogen alpha chain; fibrinogen, alpha polypeptide; fibrinogen, A alpha polypeptide

NCBI Summary for FGA

plays a role in blood coagulation; may be involved in liver regeneration [RGD, Feb 2006]

UniProt Comments for FGA

FGA: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; cell surface; rough endoplasmic reticulum; fibrinogen complex; cytoplasm; cell cortex; vesicle; external side of plasma membrane

Molecular Function: protein binding, bridging; cell adhesion molecule binding; structural molecule activity; receptor binding

Biological Process: protein polymerization; platelet activation; positive regulation of heterotypic cell-cell adhesion; cell-matrix adhesion; response to morphine; signal transduction; response to estradiol stimulus; response to genistein; cellular protein complex assembly; positive regulation of protein secretion; acute-phase response; positive regulation of vasoconstriction; response to cycloheximide; innate immune response; blood coagulation; response to calcium ion; positive regulation of exocytosis
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Research Articles on FGA

1. These results suggest that immunoreactivity of Fg in the kidney, as well as urinary excretion of Fg, serves as a sensitive and early diagnostic translational biomarker for detection of acute kidney injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FGA active protein

 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Blood Clotting Cascade Pathway antibodies  Blood Clotting Cascade Pathway Diagram
 Common Pathway antibodies  Common Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 GRB2:SOS Provides Linkage To MAPK Signaling For Intergrins Pathway antibodies  GRB2:SOS Provides Linkage To MAPK Signaling For Intergrins Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Integrin AlphaIIb Beta3 Signaling Pathway antibodies  Integrin AlphaIIb Beta3 Signaling Pathway Diagram

Organs/Tissues associated with FGA active protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >16 publications with FGA and Liver
 Lung Antibodies  >15 publications with FGA and Lung
 Kidney Antibodies  >7 publications with FGA and Kidney
 Embryonic Tissue Antibodies  >5 publications with FGA and Embryonic Tissue
 Spleen Antibodies  >3 publications with FGA and Spleen
 Colon Antibodies  >1 publications with FGA and Colon
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