Human KBTBD5 Recombinant Protein – Cat# MBS1356570

Kelch Repeat and BTB Domain-Containing Protein 5 (KBTBD5) Human Recombinant Protein

Name: KBTBD5 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1356570
Price: 1430 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1356570

MBS1356570 is a recombinant protein targeting KBTBD5. Also known as Recombinant Human Kelch repeat and BTB domain-containing protein 5 (KBTBD5). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1430 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Kelch repeat and BTB domain-containing protein 5 (KBTBD5), Recombinant Protein

Full Product Name

Recombinant Human Kelch repeat and BTB domain-containing protein 5 (KBTBD5)

Product Gene Name

KBTBD5 recombinant protein

Product Synonym Gene Name

KBTBD5

Sequence

MALGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRAG EREFPCHRLV LAACSPYFRA RFLAEPERAG ELHLEEVSPD VVAQVLHYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC VSFLQKRLCL SNCLAVFRLG LLLDCARLAV AARDFICAHF TLVARDADFL GLSADELIAI ISSDGLNVEK EEAVFEAVMR WAGSGDAEAQ AERQRALPTV FESVRCRLLP RAFLESRVER HPLVRAQPEL LRKVQMVKDA HEGRITTLRK KKKGKDGAGA KEADKGTSKA KAEEDEEAER ILPGILNDTL RFGMFLQDLI FMISEEGAVA YDPAANECYC ASLSNQVPKN HVSLVTKENQ VFVAGGLFYN EDNKEDPMSA YFLQFDHLDS EWLGMPPLPS PRCLFGLGEA LNSIYVVGGR EIKDGERCLD SVMCYDRLSF KWGESDPLPY VVYGHTVLSH MDLVYVIGGK GSDRKCLNKM CVYDPKKFEW KELAPMQTAR SLFGATVHDG RIIVAAGVTD TGLTSSAEVY SITDNKWAPF EAFPQERSSL SLVSLVGTLY AIGGFATLET ESGELVPTEL NDIWRYNEEE KKWEGVLREI AYAAGATFLP VRLNVLCLTK M

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

52,893 Da

Sequence Positions

1-621, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

615340

3D Structure

ModBase 3D Structure for Q2TBA0

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KBTBD5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KBTBD5. It may not necessarily be applicable to this product.

NCBI GI #

45593142

NCBI GeneID

131377

NCBI Accession #

NP_689606.2

UniProt Primary Accession #

Q2TBA0

UniProt Secondary Accession #

Q86SI1; Q96MR2

UniProt Related Accession #

Q2TBA0

GenBank Nucleotide #

NM_152393.3

NCBI Official Full Name

kelch-like protein 40

NCBI Official Synonym Full Names

kelch like family member 40

NCBI Official Symbol

KLHL40

NCBI Official Synonym Symbols

NEM8; SRYP; SYRP; KBTBD5

UniProt Protein Name

Kelch-like protein 40

UniProt Synonym Protein Names

Kelch repeat and BTB domain-containing protein 5; Sarcosynapsin

UniProt Gene Name

KLHL40

NCBI Protein Information

kelch-like protein 40

NCBI Summary for KBTBD5

This gene encodes a protein containing a BACK domain, a BTB/POZ domain, and 5 Kelch repeats, however, its exact function is not known. The gene and the multi-domain protein structure are conserved across different taxa, including primates, rodents, chicken and zebrafish. [provided by RefSeq, Dec 2012]

UniProt Comments for KBTBD5

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development (PubMed:23746549). The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear ().

Research Articles on KBTBD5

1. Two compound heterozygous mutations; c.602G > A(p.W201*) and c.1516A > C(p.T506P), in the Kelch-like 40 (KLHL40) gene were discovered in a family with 3 fetuses affected by fetal akinesia deformation sequence.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with KBTBD5 recombinant protein

Disease Name	Pubmed Publications
Musculoskeletal Diseases Antibodies	>1 publications with KBTBD5 and Musculoskeletal Diseases

Organs/Tissues associated with KBTBD5 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>3 publications with KBTBD5 and Muscle