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PAI-1 (Stable Mutant) (SERPINE1) Rabbit Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS135863

This stable mutant of rabbit PAI-1 contains a single conservative mutation (Isoleucine 91 to Leucine) that yields PAI-1 with an enhanced half-life as compared to the wild type. More details

$1130 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PAI-1 (stable mutant) (SERPINE1), Active Protein
Full Product Name
Rabbit PAI-1 (stable mutant)
Product Gene Name
Host
E. coli
Form/Format
Frozen liquid
Purity/Purification
>95% by SDS-PAGE analysis
Concentration
2.5 mg/ml (lot specific)
Preparation and Storage
Store at -70 degree C. Shelf Life: 3 years from delivery
Molecular Weight
43,000
Chromosome Location
chromosome: Un
3D Structure
ModBase 3D Structure for P79335
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Specific Activity
80percent active by titration with tPA
Buffer
0.05M Sodium Acetate; 0.1M NaCl; 1mM EDTA; pH 5.0
Extinction Coefficient
1

Other Notes

Small volumes of SERPINE1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SERPINE1 purchase

MBS135863 is an active protein targeting SERPINE1. Also known as Rabbit PAI-1 (stable mutant). Host: E. coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINE1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
plasminogen activator inhibitor 1
NCBI Official Symbol
SERPINE1
NCBI Official Synonym Symbols
PLANH1
UniProt Protein Name
Plasminogen activator inhibitor 1
UniProt Synonym Protein Names
Endothelial plasminogen activator inhibitor; Serpin E1
UniProt Gene Name
SERPINE1
UniProt Synonym Gene Names
PAI1; PLANH1; PAI; PAI-1
UniProt Entry Name
PAI1_PIG
NCBI Protein Information
plasminogen activator inhibitor 1; PAI; PAI-1; serpin E1; plasminogen activator inhibitor I; endothelial plasminogen activator inhibitor

UniProt Comments for SERPINE1

Function: Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis

By similarity.

Subunit structure: Forms protease inhibiting heterodimer with TMPRSS7. Interacts with VTN. Binds LRP1B; binding is followed by internalization and degradation

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the serpin family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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