• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Ubiquitin Carboxyl-Terminal Hydrolase 19 (USP19) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1360682

MBS1360682 is a recombinant protein targeting Usp19. Also known as Recombinant Rat Ubiquitin carboxyl-terminal hydrolase 19 (Usp19) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ubiquitin carboxyl-terminal hydrolase 19 (Usp19), Recombinant Protein
Full Product Name
Recombinant Rat Ubiquitin carboxyl-terminal hydrolase 19 (Usp19) , partial
Product Gene Name
Usp19 recombinant protein
Product Synonym Gene Name
Usp19
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
150,302 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q6J1Y9
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Usp19 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Usp19. It may not necessarily be applicable to this product.

NCBI GI #
48040522
NCBI GeneID
361190
NCBI Accession #
NP_001001516.1
UniProt Primary Accession #
Q6J1Y9
UniProt Related Accession #
Q6J1Y9
GenBank Nucleotide #
NM_001001516.2
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 19
NCBI Official Synonym Full Names
ubiquitin specific peptidase 19
NCBI Official Symbol
Usp19
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 19
UniProt Synonym Protein Names
Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19
UniProt Gene Name
Usp19
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 19

UniProt Comments for Usp19

Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing thier ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked ubiquitin chains ().
Show more

Research Articles on Usp19

1. High iodine intake had no discernible effects on USP20. Temporary increases in USP33 and USP19 mRNA levels were observed. The enzymes related to D2 ubiquitination change with prolonged high iodine intake. Increased D2 ubiquitination suppresses the activity of D2, causing a decrease in negative feedback of the hypothalamic-pituitary-thyroid axis.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Usp19 recombinant protein

 Disease Name  Pubmed Publications
 Muscular Atrophy Antibodies  >4 publications with Usp19 and Muscular Atrophy
 Neuromuscular Manifestations Antibodies  >4 publications with Usp19 and Neuromuscular Manifestations
 Neuromuscular Diseases Antibodies  >1 publications with Usp19 and Neuromuscular Diseases
 Vascular Diseases Antibodies  >1 publications with Usp19 and Vascular Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with Usp19 and Cell Transformation, Neoplastic
 Necrosis Antibodies  >1 publications with Usp19 and Necrosis

Organs/Tissues associated with Usp19 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >5 publications with Usp19 and Muscle
 Prostate Antibodies  >1 publications with Usp19 and Prostate
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000