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Prekallikrein (KLKB1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS136103

Mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Can be used as a… More details

$545 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Prekallikrein (KLKB1), Monoclonal Antibody
Full Product Name
Anti Mouse Prekallikrein, Clone 3A10
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
3A10-C8B4
Host
Mouse
Species Reactivity
Mouse
Form/Format
Frozen Liquid-0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6
Purity/Purification
IgG fraction
Concentration
1.0 mg/ml (lot specific)
Preparation and Storage
Store at -70 degree C.
Molecular Weight
Molecular Weight: 160,000
Target Molecular Weight: 81,000
3D Structure
ModBase 3D Structure for P26262
Source
Hybridoma Cell Culture
Antigen
Recombinant full length wild-type mouse protein (Glycosylated).
Extinction Coefficient
1.36
Epitope
Recognizes Mouse Prekallikrein
Applications Tested/Suitable for anti-KLKB1 antibody
Capture, ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-KLKB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLKB1 purchase

MBS136103 is an antibody targeting KLKB1. Also known as Anti Mouse Prekallikrein, Clone 3A10. Reactive in Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for KLKB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
plasma kallikrein preproprotein
NCBI Official Synonym Full Names
kallikrein B, plasma 1
NCBI Official Symbol
Klkb1
NCBI Official Synonym Symbols
APS; PSA; Kal3; Klk3; Kal-3
UniProt Protein Name
Plasma kallikrein
UniProt Synonym Protein Names
Fletcher factor; Kininogenin; Plasma prekallikrein
Protein Family
UniProt Gene Name
Klkb1
UniProt Synonym Gene Names
Klk3; Pk
NCBI Protein Information
plasma kallikrein

NCBI Summary for KLKB1

This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic processing to generate a disulfide-linked heterodimeric enzyme comprised of heavy and light chains. A complete deletion of the encoded protein prevents occlusive thrombus formation in mice with a minimal role in provoked bleeding. [provided by RefSeq, May 2016]
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UniProt Comments for KLKB1

The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KLKB1 antibody

Organs/Tissues associated with anti-KLKB1 antibody

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