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Squamous Cell Carcinoma Antigen Recognized by T-Cells 3 (SART3) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1361297

This protein is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Squamous cell carcinoma antigen recognized by T-cells 3 (Sart3), Recombinant Protein
Full Product Name
Recombinant Mouse Squamous cell carcinoma antigen recognized by T-cells 3 (Sart3) , partial
Product Gene Name
Sart3 recombinant protein
Product Synonym Gene Name
Sart3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
45,291 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9JLI8
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Sart3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sart3 purchase

MBS1361297 is a recombinant protein targeting Sart3. Also known as Recombinant Mouse Squamous cell carcinoma antigen recognized by T-cells 3 (Sart3) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Sart3. It may not necessarily be applicable to this product.

NCBI GI #
8394239
NCBI GeneID
53890
NCBI Accession #
NP_058622.1
UniProt Primary Accession #
Q9JLI8
UniProt Secondary Accession #
Q6ZQI2; Q8BPK9; Q8C3B7; Q8CFU9
UniProt Related Accession #
Q9JLI8
GenBank Nucleotide #
NM_016926.2
NCBI Official Full Name
squamous cell carcinoma antigen recognized by T-cells 3 isoform 2
NCBI Official Synonym Full Names
squamous cell carcinoma antigen recognized by T cells 3
NCBI Official Symbol
Sart3
NCBI Official Synonym Symbols
AU045857; mKIAA0156
UniProt Protein Name
Squamous cell carcinoma antigen recognized by T-cells 3
UniProt Synonym Protein Names
Tumor-rejection antigen SART3
Protein Family
Squamous cell carcinoma antigen
UniProt Gene Name
Sart3
UniProt Synonym Gene Names
mSART-3
NCBI Protein Information
squamous cell carcinoma antigen recognized by T-cells 3

UniProt Comments for Sart3

U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites. May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly. May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (PubMed:21447833).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Sart3 recombinant protein

 Products by Pathway  Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram

Diseases associated with Sart3 recombinant protein

 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >5 publications with Sart3 and Skin Diseases
 Breast Neoplasms Antibodies  >2 publications with Sart3 and Breast Neoplasms
 Lung Diseases Antibodies  >2 publications with Sart3 and Lung Diseases
 Porokeratosis, disseminated superficial actinic 1 Antibodies  >2 publications with Sart3 and Porokeratosis, disseminated superficial actinic 1
 Kidney Neoplasms Antibodies  >1 publications with Sart3 and Kidney Neoplasms
 Nervous System Diseases Antibodies  >1 publications with Sart3 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with Sart3 and Disease Models, Animal
 Liver Diseases Antibodies  >1 publications with Sart3 and Liver Diseases
 Headache Antibodies  >1 publications with Sart3 and Headache
 Brain Diseases Antibodies  >1 publications with Sart3 and Brain Diseases

Organs/Tissues associated with Sart3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with Sart3 and Liver
 Bone Antibodies  >2 publications with Sart3 and Bone
 Lung Antibodies  >2 publications with Sart3 and Lung
 Skin Antibodies  >2 publications with Sart3 and Skin
 Brain Antibodies  >2 publications with Sart3 and Brain
 Muscle Antibodies  >1 publications with Sart3 and Muscle
 Heart Antibodies  >1 publications with Sart3 and Heart
 Thymus Antibodies  >1 publications with Sart3 and Thymus
 Kidney Antibodies  >1 publications with Sart3 and Kidney
 Bladder Antibodies  >1 publications with Sart3 and Bladder
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