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Cytohesin-4 (CYTH4) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1362533

This protein is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is… More details

$1130 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cytohesin-4 (CYTH4), Recombinant Protein
Full Product Name
Recombinant Human Cytohesin-4 (CYTH4)
Product Gene Name
CYTH4 recombinant protein
Product Synonym Gene Name
CYTH4
Sequence
MDLCHPEPAE LSSGETEELQ RIKWHRKQLL EDIQKLKDEI ADVFAQIDCF ESAEESRMAQ KEKELCIGRK KFNMDPAKGI QYFIEHKLLT PDVQDIARFL YKGEGLNKTA IGTYLGERDP INLQVLQAFV DCHEFANLNL VQALRQFLWS FRLPGEAQKI DRMMEAFATR YCLCNPGVFQ STDTCYVLSF SIIMLNTSLH NPNVRDRPPF ERFVSMNRGI NNGSDLPEDQ LRNLFDSIKS EPFSIPEDDG NDLTHTFFNP DREGWLLKLG GRVKTWKRRW FILTDNCLYY FEFTTDKEPR GIIPLENLSV QKVDDPKKPF CLELYNPSCR GQKIKACKTD GDGRVVEGKH ESYRISATSA EERDQWIESI RASITRVPFY DLVSTRKKKI ASKQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
45,672 Da
Sequence Positions
1-394, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
606514
3D Structure
ModBase 3D Structure for Q9UIA0
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CYTH4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYTH4 purchase

MBS1362533 is a recombinant protein targeting CYTH4. Also known as Recombinant Human Cytohesin-4 (CYTH4). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for CYTH4. It may not necessarily be applicable to this product.

NCBI GI #
966708101
NCBI GeneID
27128
NCBI Accession #
NP_001304953.1
UniProt Primary Accession #
Q9UIA0
UniProt Secondary Accession #
Q5R3F9; Q9UGT6
UniProt Related Accession #
Q9UIA0
GenBank Nucleotide #
NM_001318024.1
NCBI Official Full Name
cytohesin-4 isoform 2
NCBI Official Synonym Full Names
cytohesin 4
NCBI Official Symbol
CYTH4
NCBI Official Synonym Symbols
CYT4; PSCD4; DJ63G5.1; cytohesin-4
UniProt Protein Name
Cytohesin-4
UniProt Synonym Protein Names
PH, SEC7 and coiled-coil domain-containing protein 4
Protein Family
Cytohesin
UniProt Gene Name
CYTH4
UniProt Synonym Gene Names
CYT4; PSCD4
NCBI Protein Information
cytohesin-4

NCBI Summary for CYTH4

This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
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UniProt Comments for CYTH4

Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.

Research Articles on CYTH4

1. Novel alleles were detected at the long extreme of the GTTT-repeat, at 10- and 11-repeats, in the Schizophrenia cases and controls.Three genotypes consisting of the 11-repeat allele (i.e., 11/11, 10/11, and 7/11) were detected only in the Schizophrenia patients. The frequency of the 11-repeat allele was estimated at 0.02 and 0.006 in the Schizophrenia patients and controls, respectively
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CYTH4 recombinant protein

 Reference Product  PubMed Publications
 PLEK recombinant protein  >1 publications with CYTH4 and PLEK

Pathways associated with CYTH4 recombinant protein

 Products by Pathway  Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram

Diseases associated with CYTH4 recombinant protein

 Disease Name  Pubmed Publications
 Nerve Degeneration Antibodies  >1 publications with CYTH4 and Nerve Degeneration

Organs/Tissues associated with CYTH4 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with CYTH4 and Blood
 Brain Antibodies  >2 publications with CYTH4 and Brain
 Mammary Gland Antibodies  >1 publications with CYTH4 and Mammary Gland
 Lung Antibodies  >1 publications with CYTH4 and Lung
 Uterus Antibodies  >1 publications with CYTH4 and Uterus
 Muscle Antibodies  >1 publications with CYTH4 and Muscle
 Placenta Antibodies  >1 publications with CYTH4 and Placenta
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