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Alpha N-Terminal Protein Methyltransferase 1a (METTL11A) Bovine Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1367288

MBS1367288 is a recombinant protein targeting METTL11A. Also known as Recombinant Bovine Alpha N-terminal protein methyltransferase 1A (METTL11A). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$880 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alpha N-terminal protein methyltransferase 1A (METTL11A), Recombinant Protein
Full Product Name
Recombinant Bovine Alpha N-terminal protein methyltransferase 1A (METTL11A)
Product Synonym Gene Name
METTL11A
Sequence
MTSEVIEDEK QFYSKAKTYW KEVPATVDGM LGGYGHISSI DINSSRKFLQ RFLREGQNKT GTSYALDCGA GIGRITKRLL LPLFGVVDMV DVTEDFLVKA KTYLGEEGKR VRNFFCCGLQ DFSPEPQSYD VIWIQWVIGH LTDQHLAEFL RRCKRGLRPN GIIVIKDNMA QEGVILDDVD SSVCRALDVV HRIVRSAGLS LLAQERQENL PDEIYHVYSL ALR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
25,289 Da
Sequence Positions
1-223, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q2T9N3
Species
Bovine
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of METTL11A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for METTL11A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
N-terminal Xaa-Pro-Lys N-methyltransferase 1
NCBI Official Synonym Full Names
N-terminal Xaa-Pro-Lys N-methyltransferase 1
NCBI Official Symbol
NTMT1
NCBI Official Synonym Symbols
NTM1A; C9orf32; METTL11A; C11H9orf32
UniProt Protein Name
N-terminal Xaa-Pro-Lys N-methyltransferase 1
UniProt Synonym Protein Names
Alpha N-terminal protein methyltransferase 1A; Methyltransferase-like protein 11A; X-Pro-Lys N-terminal protein methyltransferase 1A; NTM1A
UniProt Gene Name
NTMT1
UniProt Synonym Gene Names
METTL11A; NTM1A
NCBI Protein Information
N-terminal Xaa-Pro-Lys N-methyltransferase 1

UniProt Comments for METTL11A

Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1). Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with METTL11A recombinant protein

 Reference Product  PubMed Publications
 METTL11A recombinant protein  >1 publications with METTL11A and METTL11A
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