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80 Kda MCM3-Associated Protein (MCM3AP) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1367529

The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. This protein is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
80 kDa MCM3-associated protein (Mcm3ap), Recombinant Protein
Full Product Name
Recombinant Mouse 80 kDa MCM3-associated protein (Mcm3ap) , partial
Product Gene Name
Mcm3ap recombinant protein
Product Synonym Gene Name
Mcm3ap
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
217,363 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9WUU9
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mcm3ap recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mcm3ap purchase

MBS1367529 is a recombinant protein targeting Mcm3ap. Also known as Recombinant Mouse 80 kDa MCM3-associated protein (Mcm3ap) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Mcm3ap. It may not necessarily be applicable to this product.

NCBI GI #
109627648
NCBI GeneID
54387
NCBI Accession #
NP_062307.2
UniProt Primary Accession #
Q9WUU9
UniProt Secondary Accession #
Q7TS87
UniProt Related Accession #
Q9WUU9
GenBank Nucleotide #
NM_019434.2
NCBI Official Full Name
germinal-center associated nuclear protein
NCBI Official Synonym Full Names
minichromosome maintenance complex component 3 associated protein
NCBI Official Symbol
Mcm3ap
NCBI Official Synonym Symbols
GANP; mKIAA0572
UniProt Protein Name
Germinal-center associated nuclear protein
UniProt Synonym Protein Names
GC-associated DNA primase
Protein Family
Germinal-center associated nuclear protein
UniProt Gene Name
Mcm3ap
UniProt Synonym Gene Names
Ganp; Map80; GANP
NCBI Protein Information
germinal-center associated nuclear protein

UniProt Comments for Mcm3ap

Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (). Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells.
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Research Articles on Mcm3ap

1. These results indicated that the GANP protein is associated with breast cancer resistance.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Mcm3ap recombinant protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >3 publications with Mcm3ap and Necrosis
 Cell Transformation, Neoplastic Antibodies  >2 publications with Mcm3ap and Cell Transformation, Neoplastic
 Congenital Abnormalities Antibodies  >2 publications with Mcm3ap and Congenital Abnormalities
 Inflammation Antibodies  >2 publications with Mcm3ap and Inflammation
 Liver Diseases Antibodies  >1 publications with Mcm3ap and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with Mcm3ap and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with Mcm3ap and Liver Neoplasms

Organs/Tissues associated with Mcm3ap recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with Mcm3ap and Blood
 Liver Antibodies  >3 publications with Mcm3ap and Liver
 Brain Antibodies  >3 publications with Mcm3ap and Brain
 Spleen Antibodies  >2 publications with Mcm3ap and Spleen
 Thymus Antibodies  >1 publications with Mcm3ap and Thymus
 Lung Antibodies  >1 publications with Mcm3ap and Lung
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