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Oxysterol-Binding Protein-Related Protein 2 (OSBPL2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1367962

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some… More details

$1260 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Oxysterol-binding protein-related protein 2 (OSBPL2), Recombinant Protein
Full Product Name
Recombinant Human Oxysterol-binding protein-related protein 2 (OSBPL2)
Product Gene Name
OSBPL2 recombinant protein
Product Synonym Gene Name
OSBPL2
Sequence
MNGEEEFFDA VTGFDSDNSS GEFSEANQKV TGMIDLDTSK NNRIGKTGER PSQENGIQKH RTSLPAPMFS RSDFSVWTIL KKCVGLELSK ITMPIAFNEP LSFLQRITEY MEHVYLIHRA SCQPQPLERM QSVAAFAVSA VASQWERTGK PFNPLLGETY ELIREDLGFR FISEQVSHHP PISAFHSEGL NHDFLFHGSI YPKLKFWGKS VEAEPRGTIT LELLKHNEAY TWTNPTCCVH NVIIGKLWIE QYGTVEILNH RTGHKCVLHF KPCGLFGKEL HKVEGHIQDK NKKKLFMIYG KWTECLWGID PVSYESFKKQ ERRGDHLRKA KLDEDSGKAD SDVADDVPVA QETVQVIPGS KLLWRINTRP PNSAQMYNFT SFTVSLNELE TGMEKTLPPT DCRLRPDIRG MENGNMDLAS QEKERLEEKQ REARRERAKE EAEWQTRWFY PGNNPYTGTP DWLYAGDYFE RNFSDCPDIY
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
53,971 Da
Sequence Positions
1-480, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
606731
3D Structure
ModBase 3D Structure for Q9H1P3
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of OSBPL2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSBPL2 purchase

MBS1367962 is a recombinant protein targeting OSBPL2. Also known as Recombinant Human Oxysterol-binding protein-related protein 2 (OSBPL2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for OSBPL2. It may not necessarily be applicable to this product.

NCBI GI #
7662298
NCBI GeneID
9885
NCBI Accession #
NP_055650.1
UniProt Primary Accession #
Q9H1P3
UniProt Secondary Accession #
Q6IBT0; Q9BZB1; Q9Y4B8; A8K736
UniProt Related Accession #
Q9H1P3
GenBank Nucleotide #
NM_014835.3
NCBI Official Full Name
oxysterol-binding protein-related protein 2 isoform 1
NCBI Official Synonym Full Names
oxysterol binding protein like 2
NCBI Official Symbol
OSBPL2
NCBI Official Synonym Symbols
ORP2; ORP-2; DFNA67; DNFA67
UniProt Protein Name
Oxysterol-binding protein-related protein 2
Protein Family
Oxysterol-binding protein-related protein
UniProt Gene Name
OSBPL2
UniProt Synonym Gene Names
KIAA0772; ORP2; ORP-2; OSBP-related protein 2
NCBI Protein Information
oxysterol-binding protein-related protein 2

NCBI Summary for OSBPL2

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]
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UniProt Comments for OSBPL2

Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (PubMed:11279184). Binds 25-hydroxycholesterol (PubMed:17428193).

Research Articles on OSBPL2

1. a novel role for ORP2 in regulating steroidogenic capacity and cholesterol homeostasis in the adrenal cortex

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with OSBPL2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >3 publications with OSBPL2 and Ovary
 Adrenal Gland Antibodies  >1 publications with OSBPL2 and Adrenal Gland
 Adipose Tissue Antibodies  >1 publications with OSBPL2 and Adipose Tissue
 Blood Antibodies  >1 publications with OSBPL2 and Blood
 Eye Antibodies  >1 publications with OSBPL2 and Eye
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