Human KDM3B Recombinant Protein – Cat# MBS1368346

Lysine-Specific Demethylase 3b (KDM3B), Partial (KDM3B) Human Recombinant Protein

Name: KDM3B Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1368346
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1368346

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lysine-specific demethylase 3B (KDM3B), partial, Recombinant Protein

Full Product Name

Recombinant Human Lysine-specific demethylase 3B (KDM3B), partial

Product Gene Name

KDM3B recombinant protein

Product Synonym Gene Name

KDM3B; C5orf7; JHDM2B; JMJD1B; KIAA1082

Product Synonym Names

Lysine-specific demethylase 3B; EC=1.14.11.-; JmjC domain-containing histone demethylation protein 2B; Jumonji domain-containing protein 1B; Nuclear protein 5qNCA

Sequence

MPTRFEDLME NLPLPEYTKR DGRLNLASRL PSYFVRPDLG PKMYNAYGLI TAEDRRVGTT NLHLDVSDAV NVMVYVGIPI GEGAHDEEVL KTIDEGDADE VTKQRIHDGK EKPGALWHIY AAKDAEKIRE LLRKVGEEQG QENPPDHDPI HDQSWYLDQT LRKRLYEEYG VQGWAIVQFL GDAVFIPAGA PHQVHNLYSC IKVAEDFVSP EHVKHCFRLT QEFR

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

45.6 kDa

Sequence Positions

1498-1721AA; Partial

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

609373

3D Structure

ModBase 3D Structure for Q7LBC6

Species

Homo sapiens (Human)

Production Note

Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.

Product Categories/Family for KDM3B recombinant protein

Epigenetics and Nuclear Signaling

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KDM3B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KDM3B purchase

MBS1368346 is a recombinant protein targeting KDM3B. Also known as Recombinant Human Lysine-specific demethylase 3B (KDM3B), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for KDM3B. It may not necessarily be applicable to this product.

NCBI GI #

38372909

NCBI GeneID

51780

NCBI Accession #

NP_057688.2

UniProt Primary Accession #

Q7LBC6

UniProt Secondary Accession #

Q9BVH6; Q9BW93; Q9BZ52; Q9NYF4; Q9UPS0; A6H8X7

UniProt Related Accession #

Q7LBC6

GenBank Nucleotide #

NM_016604.3

NCBI Official Full Name

lysine-specific demethylase 3B

NCBI Official Synonym Full Names

lysine (K)-specific demethylase 3B

NCBI Official Symbol

KDM3B

NCBI Official Synonym Symbols

5qNCA; NET22; C5orf7; JMJD1B

UniProt Protein Name

Lysine-specific demethylase 3B

UniProt Synonym Protein Names

JmjC domain-containing histone demethylation protein 2B; Jumonji domain-containing protein 1B; Nuclear protein 5qNCA

Protein Family

Lysine-specific demethylase

UniProt Gene Name

KDM3B

UniProt Synonym Gene Names

C5orf7; JHDM2B; JMJD1B; KIAA1082

UniProt Entry Name

KDM3B_HUMAN

NCBI Protein Information

lysine-specific demethylase 3B; nuclear protein 5qNCA; jumonji domain containing 1B; jumonji domain-containing protein 1B; jmjC domain-containing histone demethylation protein 2B

UniProt Comments for KDM3B

JMJD1B: a ubiquitous protein demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. Three alternatively spliced isoforms have been reported.

Protein type: Oxidoreductase; Demethylase; EC 1.14.11.-

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: nucleoplasm

Molecular Function: dioxygenase activity; metal ion binding

Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; regulation of transcription, DNA-dependent; chromatin modification

Research Articles on KDM3B

1. High expression of KDM3B and KDM5A is associated with a better prognosis (no recurrence after mastectomy p=0.005 and response to docetaxel p=0.005)in breast cancer patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with KDM3B recombinant protein

Products by Pathway	Pathway Diagram
Chromatin Modifying Enzymes Pathway antibodies	Chromatin Modifying Enzymes Pathway Diagram
Chromatin Organization Pathway antibodies	Chromatin Organization Pathway Diagram
HDMs Demethylate Histones Pathway antibodies	HDMs Demethylate Histones Pathway Diagram

Diseases associated with KDM3B recombinant protein

Disease Name	Pubmed Publications
Anoxia Antibodies	>1 publications with KDM3B and Anoxia

Organs/Tissues associated with KDM3B recombinant protein

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>1 publications with KDM3B and Prostate
Blood Antibodies	>1 publications with KDM3B and Blood
Liver Antibodies	>1 publications with KDM3B and Liver
Placenta Antibodies	>1 publications with KDM3B and Placenta
Kidney Antibodies	>1 publications with KDM3B and Kidney
Muscle Antibodies	>1 publications with KDM3B and Muscle
Lung Antibodies	>1 publications with KDM3B and Lung