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RNA-Binding Protein 38 (RBM38) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1373745

MBS1373745 is a recombinant protein targeting RBM38. Also known as Recombinant Human RNA-binding protein 38 (RBM38). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$905 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RNA-binding protein 38 (RBM38), Recombinant Protein
Full Product Name
Recombinant Human RNA-binding protein 38 (RBM38)
Product Gene Name
RBM38 recombinant protein
Product Synonym Gene Name
RBM38
Sequence
MLLQPAPCAP SAGFPRPLAA PGAMHGSQKD TTFTKIFVGG LPYHTTDASL RKYFEGFGDI EEAVVITDRQ TGKSRGYGFV TMADRAAAER ACKDPNPIID GRKANVNLAY LGAKPRSLQT GFAIGVQQLH PTLIQRTYGL TPHYIYPPAI VQPSVVIPAA PVPSLSSPYI EYTPASPAYA QYPPATYDQY PYAASPATAA SFVGYSYPAA VPQALSAAAP AGTTFVQYQA PQLQPDRMQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
12,914 Da
Sequence Positions
1-239, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
612428
3D Structure
ModBase 3D Structure for Q9H0Z9
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RBM38 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RBM38. It may not necessarily be applicable to this product.

NCBI GI #
619534169
NCBI GeneID
55544
NCBI Accession #
NP_001278709.1
UniProt Primary Accession #
Q9H0Z9
UniProt Secondary Accession #
Q15350; Q15351; Q9BYK3; Q9BYK4; A6NDK1; A6NMU6
UniProt Related Accession #
Q9H0Z9
GenBank Nucleotide #
NM_001291780.1
NCBI Official Full Name
RNA-binding protein 38 isoform c
NCBI Official Synonym Full Names
RNA binding motif protein 38
NCBI Official Symbol
RBM38
NCBI Official Synonym Symbols
RNPC1; SEB4B; SEB4D; HSRNASEB; dJ800J21.2
UniProt Protein Name
RNA-binding protein 38
UniProt Synonym Protein Names
CLL-associated antigen KW-5; HSRNASEB; RNA-binding motif protein 38; RNA-binding region-containing protein 1; ssDNA-binding protein SEB4
Protein Family
RNA-binding protein
UniProt Gene Name
RBM38
UniProt Synonym Gene Names
RNPC1; SEB4
NCBI Protein Information
RNA-binding protein 38

UniProt Comments for RBM38

RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
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Research Articles on RBM38

1. Results report that RBM38 mediates direct inhibition of c-Myc expression, which in turn suppresses RBM38 expression. Thus, it can be concluded that RBM38 and c-Myc form a unique mutually antagonistic RBM38-c-Myc loop in breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RBM38 recombinant protein

 Reference Product  PubMed Publications
 TP53 recombinant protein  >4 publications with RBM38 and TP53
 MDM2 recombinant protein  >2 publications with RBM38 and MDM2
 ELAVL1 recombinant protein  >2 publications with RBM38 and ELAVL1
 TP63 recombinant protein  >1 publications with RBM38 and TP63

Diseases associated with RBM38 recombinant protein

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >6 publications with RBM38 and Breast Neoplasms
 Carcinoma Antibodies  >3 publications with RBM38 and Carcinoma
 Neoplasm Metastasis Antibodies  >2 publications with RBM38 and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >2 publications with RBM38 and Ovarian Neoplasms
 Adenocarcinoma Antibodies  >2 publications with RBM38 and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >1 publications with RBM38 and Neoplasms, Experimental
 Congenital Abnormalities Antibodies  >1 publications with RBM38 and Congenital Abnormalities
 Neural Tube Defects Antibodies  >1 publications with RBM38 and Neural Tube Defects
 Liver Diseases Antibodies  >1 publications with RBM38 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with RBM38 and Carcinoma, Hepatocellular

Organs/Tissues associated with RBM38 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with RBM38 and Blood
 Muscle Antibodies  >3 publications with RBM38 and Muscle
 Embryonic Tissue Antibodies  >1 publications with RBM38 and Embryonic Tissue
 Lymph Node Antibodies  >1 publications with RBM38 and Lymph Node
 Skin Antibodies  >1 publications with RBM38 and Skin
 Brain Antibodies  >1 publications with RBM38 and Brain
 Lymph Antibodies  >1 publications with RBM38 and Lymph
 Eye Antibodies  >1 publications with RBM38 and Eye
 Liver Antibodies  >1 publications with RBM38 and Liver
 Lung Antibodies  >1 publications with RBM38 and Lung
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