Human U2AF1L4 Recombinant Protein – Cat# MBS1375574

Splicing Factor U2AF 26 Kda Subunit (U2AF1L4) Human Recombinant Protein

Name: U2AF1L4 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1375574
Price: 545 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1375574

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection.… More details

$545 / 0.02 mg (Baculovirus) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Splicing factor U2AF 26 kDa subunit (U2AF1L4), Recombinant Protein

Full Product Name

Recombinant Human Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Product Gene Name

U2AF1L4 recombinant protein

Product Synonym Gene Name

U2AF1L4; U2AF1-RS3; U2AF1L3

Product Synonym Names

Splicing factor U2AF 26 kDa subunit; U2 auxiliary factor 26; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2AF1-like protein 3

Sequence

MAEYLASIFG TEKDKVNCSF YFKIGVCRHG DRCSRLHNKP TFSQEVFTEL QEKYGEIEEM NVCDNLGDHL VGNVYVKFRR EEDGERAVAE LSNRWFNGQA VHGNVPEVAS ATSCICGPFP RTSRGSSMGG DPGAGHPRGS ILATIPERGT IGVPLITGMA ASEALAPLPF TPNRDRCSWQ DLSSKPPSLS CPILPRLPGS IM

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

49 kDa

Sequence Positions

1-202aa; Full Length of Isoform 2

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

601080

3D Structure

ModBase 3D Structure for Q8WU68

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of U2AF1L4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for U2AF1L4 purchase

MBS1375574 is a recombinant protein targeting U2AF1L4. Also known as Recombinant Human Splicing factor U2AF 26 kDa subunit (U2AF1L4). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for U2AF1L4. It may not necessarily be applicable to this product.

NCBI GI #

94536809

NCBI GeneID

199746

NCBI Accession #

NP_001035515.1

UniProt Primary Accession #

Q8WU68

UniProt Secondary Accession #

Q56UU3; A6NKI8

UniProt Related Accession #

Q8WU68

GenBank Nucleotide #

NM_001040425.2

NCBI Official Full Name

splicing factor U2AF 26 kDa subunit isoform 1

NCBI Official Synonym Full Names

U2 small nuclear RNA auxiliary factor 1-like 4

NCBI Official Symbol

U2AF1L4

NCBI Official Synonym Symbols

U2af26; U2AF1L3; U2AF1RS3; U2AF1-RS3; U2AF1L3V1

UniProt Protein Name

Splicing factor U2AF 26 kDa subunit

UniProt Synonym Protein Names

U2 auxiliary factor 26; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2AF1-like protein 3

Protein Family

Splicing factor

UniProt Gene Name

U2AF1L4

UniProt Synonym Gene Names

U2AF1-RS3; U2AF1L3; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2AF1-like protein 3

UniProt Entry Name

U2AF4_HUMAN

NCBI Protein Information

splicing factor U2AF 26 kDa subunit; U2AF1-like protein 3; U2 auxiliary factor 26; U2 small nuclear RNA auxiliary factor 1-like 3; U2(RNU2) small nuclear RNA auxiliary factor 1-like 3; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3

UniProt Comments for U2AF1L4

U2AF1L4: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site. Belongs to the splicing factor SR family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: spliceosome; cytoplasm; nuclear speck

Molecular Function: RNA binding; metal ion binding; nucleotide binding

Biological Process: RNA splicing; mRNA processing

Research Articles on U2AF1L4

1. a 269 bp region located between the PSENEN and U2AF1L4 human genes is a genuine bidirectional promoter regulating a concerted divergent transcription of these genes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with U2AF1L4 recombinant protein

Reference Product	PubMed Publications
GFI1 recombinant protein	>1 publications with U2AF1L4 and GFI1

Organs/Tissues associated with U2AF1L4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with U2AF1L4 and Brain
Heart Antibodies	>1 publications with U2AF1L4 and Heart
Blood Antibodies	>1 publications with U2AF1L4 and Blood
Lung Antibodies	>1 publications with U2AF1L4 and Lung