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Protein Phyllopod (phyl) Drosophila Melanogaster Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1376394

MBS1376394 is a recombinant protein targeting phyl. Also known as Recombinant Drosophila melanogaster Protein phyllopod (phyl). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1135 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Protein phyllopod (phyl), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Protein phyllopod (phyl)
Product Gene Name
phyl recombinant protein
Product Synonym Gene Name
phyl
Sequence
MSTNQQQQAN PSAAVAAPAA SSEYLKRTCL ICGCHTNQTI NIYEPRSGPN IVQLIQAKFK FQPLNEDKFL CFSCNNWLIN WHSLQAVNSN EAESQSQSPS HMGNSVLQQE RTKLRPVAMV RPTVRVQPQS QPQLQPQVPI NPTPAPIVYS KRRASRRSAS VSRMSRVLRQ CCVESLRRSP KKRNQQSVFV CLRPQGQKRS NAICKVECVA PRRKPVERLV KDVAATATPT PVLNTQSTPT YQRFPQPSVD GKVVAMFRRL GTTLSREEPA AYSAESNPAC SKLPQIMSPL KEAPRWTRDL DDDEILLEFD TAISEVLPTA RYQVTHEENK ENQQAQEMEL ELEEEEEVDG RAELEVVQEA EAPLEPQSHH KQGNSHQNSH QASIQLAGLR LPMGLSISLV
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
44,842 Da
Sequence Positions
1-400, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q27934
Species
Drosophila melanogaster (Fruit fly)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of phyl recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for phyl. It may not necessarily be applicable to this product.

NCBI GI #
24653649
NCBI GeneID
36606
NCBI Accession #
NP_725394.1
UniProt Primary Accession #
Q27934
UniProt Secondary Accession #
Q9V721; C0PV22
UniProt Related Accession #
Q27934
GenBank Nucleotide #
NM_166055.2
NCBI Official Full Name
phyllopod
NCBI Official Synonym Full Names
phyllopod
NCBI Official Symbol
phyl
NCBI Official Synonym Symbols
CG10108; D(DmcycE[JP])2.2; DmelCG10108; phy1; Phyl; PHYL; SR2-3; Su(Raf)2C
UniProt Protein Name
Protein phyllopod
Protein Family
Protein phyllopod
UniProt Gene Name
phyl
NCBI Protein Information
CG10108 gene product from transcript CG10108-RA

UniProt Comments for phyl

Essential adapter component of E3 ubiquitin ligase complexes; involved in R7 photoreceptor cell differentiation, embryonic nervous system, external sensory organ development and specification of particular muscles. E3 ubiquitin ligase complexes mediate ubiquitination and subsequent proteasomal degradation of target proteins. Required for specification of R7 photoreceptor cell fate in the eye by participating in the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk), a general inhibitor of photoreceptor differentiation. Acts downstream of Notch signaling to specify the fate of the SOP (sensory organ precursor) cells and their progeny, probably via the sina-mediated proteasomal degradation of ttk. Its restricted pattern of expression, upon Notch and Ras signaling pathways, suggests that it acts as a key determinant in E3 complexes to trigger protein proteolysis in appropriate cells.
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Research Articles on phyl

1. Notch and Wingless signalling are regulated by phyllopod, a transcriptional target of the EGFR pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with phyl recombinant protein

 Reference Product  PubMed Publications
 ttk recombinant protein  >5 publications with phyl and ttk
 sina recombinant protein  >5 publications with phyl and sina
 ago recombinant protein  >1 publications with phyl and ago

Diseases associated with phyl recombinant protein

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with phyl and Kidney Diseases
 Brain Diseases Antibodies  >1 publications with phyl and Brain Diseases
 Bone Diseases, Metabolic Antibodies  >1 publications with phyl and Bone Diseases, Metabolic

Organs/Tissues associated with phyl recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Head Antibodies  >4 publications with phyl and Head
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