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Zinc Finger and BTB Domain-Containing Protein 17 (ZBTB17) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1377456

This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18. More details

$1675 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Zinc finger and BTB domain-containing protein 17 (Zbtb17), Recombinant Protein
Full Product Name
Recombinant Mouse Zinc finger and BTB domain-containing protein 17 (Zbtb17)
Product Gene Name
Zbtb17 recombinant protein
Product Synonym Gene Name
Zbtb17
Sequence
MDFPQHSQRV LEQLNQQRQL GLLCDCTFVV DGVDFKAHKA VLAACSEYFK MLFVDQKDVV HLDISNAAGL GQVLEFMYTA KLSLSPENVD DVLAVASFLQ MQDIVTACHT LKSLAEPSST TGESADASAV EGGDKRAKDE KAAATMLSRL DQARGSSSTG PGRELKEERG GQAESASSGA EQTEKADAPR EPPPVELKPD PTSSMAAAEA EALSESSEQE MEVEPASKGE DGQEEEGAGP ATVKEEGMHL DNGEPPEENE ESAGTDSGQE LGMEGQNLRS GTYGDRTESK AYGSIIHKCE DCGKEFTHTG NFKRHIRIHT GEKPFSCREC SKAFSDPAAC KAHEKTHSPL KPYGCEECGK SYRLISLLNL HKKRHSGEAR YRCGDCGKLF TTSGNLKRHQ LVHSGQKPYQ CDYCGRSFSD PTSKMRHLET HDTDKEHKCP HCDKKFNQVG NLKAHLKIHI ADGPLKCREC GKQFTTSGNL KRHLRIHSGE KPYVCTHCQR QFADPGALQR HVRIHTGEKP CQCVICGKAF TQASSLIAHV RQHTGEKPYV CERCGKRFVQ SSQLANHIRH HDNIRPHKCS VCSKAFVNVG DLSKHIIIHT GEKPYLCDKC GRGFNRVDNL RSHVKTVHQG KAGIKILEPE EGGEVSVVTV DDMVTLATEA LAATAVTQLT VVPVGAAVTA DETEVLKAEI SKAVKQVQEE DPNTHILYAC DSCGDKFLDA NSLAQHVRIH TAQALVMFQT DADFYQQYGP GSTWPAGQML QAGELVFRPR DGTEGQPTLA ESPPTAPDCL PPAE
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
86,758 Da
Sequence Positions
1-794, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q60821
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Zbtb17 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Zbtb17 purchase

MBS1377456 is a recombinant protein targeting Zbtb17. Also known as Recombinant Mouse Zinc finger and BTB domain-containing protein 17 (Zbtb17). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Zbtb17. It may not necessarily be applicable to this product.

NCBI GI #
171919772
NCBI GeneID
22642
NCBI Accession #
NP_033567.2
UniProt Primary Accession #
Q60821
UniProt Secondary Accession #
Q60699; A2ADB9
UniProt Related Accession #
Q60821
GenBank Nucleotide #
NM_009541.2
NCBI Official Full Name
zinc finger and BTB domain-containing protein 17
NCBI Official Synonym Full Names
zinc finger and BTB domain containing 17
NCBI Official Symbol
Zbtb17
NCBI Official Synonym Symbols
Lp-1; Miz1; mZ13; Zfp100; AA589413
UniProt Protein Name
Zinc finger and BTB domain-containing protein 17
UniProt Synonym Protein Names
LP-1; Polyomavirus late initiator promoter-binding protein; Zinc finger protein 100; Zfp-100; Zinc finger protein 151; Zinc finger protein Z13
Protein Family
Zinc finger and BTB domain-containing protein
UniProt Gene Name
Zbtb17
UniProt Synonym Gene Names
Zfp100; Znf151; Zfp-100
NCBI Protein Information
zinc finger and BTB domain-containing protein 17

UniProt Comments for Zbtb17

Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 ().
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Research Articles on Zbtb17

1. rather than via E-Box binding, cMyc acts in the dorsal neural tube by interacting with another transcription factor, Miz1, to promote self-renewal. The finding that cMyc operates in a non-canonical manner in the premigratory neural crest highlights the importance of examining its role at specific time points and in an in vivo context.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Zbtb17 recombinant protein

 Reference Product  PubMed Publications
 Dnmt3b recombinant protein  >1 publications with Zbtb17 and Dnmt3b

Pathways associated with Zbtb17 recombinant protein

 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Signaling Pathway antibodies  Cell Cycle Signaling Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram

Diseases associated with Zbtb17 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >17 publications with Zbtb17 and Neoplasms
 Necrosis Antibodies  >3 publications with Zbtb17 and Necrosis
 Neoplasms, Neuroepithelial Antibodies  >3 publications with Zbtb17 and Neoplasms, Neuroepithelial
 Colonic Neoplasms Antibodies  >2 publications with Zbtb17 and Colonic Neoplasms
 Gastrointestinal Diseases Antibodies  >2 publications with Zbtb17 and Gastrointestinal Diseases
 Liver Neoplasms Antibodies  >2 publications with Zbtb17 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with Zbtb17 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >1 publications with Zbtb17 and Liver Diseases
 Anemia Antibodies  >1 publications with Zbtb17 and Anemia
 Neoplasms, Experimental Antibodies  >1 publications with Zbtb17 and Neoplasms, Experimental

Organs/Tissues associated with Zbtb17 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4 publications with Zbtb17 and Bone
 Bone Marrow Antibodies  >4 publications with Zbtb17 and Bone Marrow
 Liver Antibodies  >3 publications with Zbtb17 and Liver
 Thymus Antibodies  >2 publications with Zbtb17 and Thymus
 Kidney Antibodies  >2 publications with Zbtb17 and Kidney
 Inner Ear Antibodies  >1 publications with Zbtb17 and Inner Ear
 Skin Antibodies  >1 publications with Zbtb17 and Skin
 Mammary Gland Antibodies  >1 publications with Zbtb17 and Mammary Gland
 Brain Antibodies  >1 publications with Zbtb17 and Brain
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