Human PPAN Recombinant Protein – Cat# MBS1380223

Suppressor of SWI4 1 Homolog (PPAN) Human Recombinant Protein

Name: PPAN Recombinant Protein; Suppressor of SWI4 1 Homolog; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1380223
Price: 385 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1380223

This protein is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell… More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Suppressor of SWI4 1 homolog (PPAN), Recombinant Protein

Full Product Name

Recombinant Human Suppressor of SWI4 1 homolog (PPAN)

Product Gene Name

PPAN recombinant protein

Product Synonym Gene Name

PPAN

Sequence

MGQSGRSRHQ KRARAQAQLR NLEAYAANPH SFVFTRGCTG RNIRQLSLDV RRVMEPLTAS RLQVRKKNSL KDCVAVAGPL GVTHFLILSK TETNVYFKLM RLPGGPTLTF QVKKYSLVRD VVSSLRRHRM HEQQFAHPPL LVLNSFGPHG MHVKLMATMF QNLFPSINVH KVNLNTIKRC LLIDYNPDSQ ELDFRHYSIK VVPVGASRGM KKLLQEKFPN MSRLQDISEL LATGAGLSES EAEPDGDHNI TELPQAVAGR GNMRAQQSAV RLTEIGPRMT LQLIKVQEGV GEGKVMFHSF VSKTEEELQA ILEAKEKKLR LKAQRQAQQA QNVQRKQEQR EAHRKKSLEG MKKARVGGSD EEASGIPSRT ASLELGEDDD EQEDDDIEYF CQAVGEAPSE DLFPEAKQKR LAKSPGRKRK RWEMDRGRGR LCDQKFPKTK DKSQGAQARR GPRGASRDGG RGRGRGRPGK RVA

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

55.2 kDa

Sequence Positions

1-473aa, full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

607793

3D Structure

ModBase 3D Structure for Q9NQ55

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PPAN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPAN purchase

MBS1380223 is a recombinant protein targeting PPAN. Also known as Recombinant Human Suppressor of SWI4 1 homolog (PPAN). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for PPAN. It may not necessarily be applicable to this product.

NCBI GI #

99028871

NCBI GeneID

692312

NCBI Accession #

NP_001035754.1

UniProt Primary Accession #

Q9NQ55

UniProt Secondary Accession #

Q9BW97; Q9H170; C9J3F9

GenBank Nucleotide #

NM_001040664.2

NCBI Official Full Name

PPAN-P2RY11 protein isoform 1

NCBI Official Synonym Full Names

PPAN-P2RY11 readthrough

NCBI Official Symbol

PPAN-P2RY11

UniProt Protein Name

Suppressor of SWI4 1 homolog

UniProt Synonym Protein Names

Brix domain-containing protein 3; Peter Pan homolog

Protein Family

Peter Pan-like protein

UniProt Gene Name

PPAN

UniProt Synonym Gene Names

BXDC3; SSF1; Ssf-1

NCBI Protein Information

PPAN-P2RY11 protein

NCBI Summary for PPAN

This locus represents naturally occurring read-through transcription between the adjacent PPAN and P2RY11 genes. Alternative splicing results in two transcript variants, one of which encodes a fusion protein that shares sequence identity with each individual gene product. This transcript is found to be ubiquitously expressed and is up-regulated by agents inducing granulocytic differentiation. However, its functional significance in vivo remains unclear. [provided by RefSeq, Nov 2010]

UniProt Comments for PPAN

May have a role in cell growth.MiscellaneousA chimeric transcript, characterized by the first third of PPAN exon 12 joined to P2RY11 exon 2, has been detected. It is possibly produced by trans-splicing. The chimeric transcript is widely expressed and can be induced by retinoic acid during the granulocytic differentiation of the HL-60 cell line. The resulting chimeric protein shows a much lower activity than the non-chimeric P2RY11 gene product, but qualitatively indistinguishable (PubMed:11278528).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PPAN recombinant protein

Reference Product	PubMed Publications
P2RY11 recombinant protein	>1 publications with PPAN and P2RY11

Pathways associated with PPAN recombinant protein

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Nucleotide-like (purinergic) Receptors Pathway antibodies	Nucleotide-like (purinergic) Receptors Pathway Diagram
P2Y Receptors Pathway antibodies	P2Y Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with PPAN recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>5 publications with PPAN and Nervous System Diseases
Cardiovascular Diseases Antibodies	>2 publications with PPAN and Cardiovascular Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with PPAN and Carcinoma, Hepatocellular

Organs/Tissues associated with PPAN recombinant protein

Organ/Tissue Name	Pubmed Publications
Placenta Antibodies	>1 publications with PPAN and Placenta